400-91-9

Usage

Uses

Used in Organic Chemistry:
3-Bromo-4,6-dinitrofluorobenzene is used as a reagent for the introduction of a 2,4-dinitrophenyl (DNP) group onto amines, alcohols, and thiols. Its strong electrophilic nature allows it to readily react with nucleophiles, forming stable dinitrophenyl derivatives.
Used in Analytical and Biochemical Applications:
The stable dinitrophenyl derivatives formed by the reaction of 3-bromo-4,6-dinitrofluorobenzene with nucleophiles are often used as a means of detecting and quantifying the presence of amines, alcohols, and thiols in various analytical and biochemical applications.
Used in Synthesis of Dinitrophenyl Compounds:
3-Bromo-4,6-dinitrofluorobenzene serves as a starting material for the synthesis of other dinitrophenyl compounds, which may have various applications in different fields.
Used in Pesticide Industry:
3-Bromo-4,6-dinitrofluorobenzene has been studied for its potential as a pesticide, although its toxic nature requires careful handling and consideration of safety measures.

InChI:InChI=1/C6H2BrFN2O4/c7-3-1-4(8)6(10(13)14)2-5(3)9(11)12/h1-2H

Upstream product

• 1073-06-9 3-fluorobromobenzene 
• 700-36-7 2-bromo-4-fluoronitrobenzene 
• 166818-71-9 4-bromo-6-fluorobenzene-1,3-diamine 

Downstream Products

• 616-74-0 4,6-dinitroresorcinol 
• 116632-29-2 5-bromo-2,4-dinitro-phenol 
• 1226527-06-5 2-(benzothiazole-2-sulfonyl)-2-(5-bromo-2,4-dinitro-phenyl)-1-phenyl-ethanone 
• 1226527-27-0 2-(5-chloro-benzothiazole-2-sulfonyl)-2-(5-bromo-2,4-dinitro-phenyl)-1-phenyl-ethanone 
• 1185916-56-6 C₁₀H₅FN₂O₄S 
• 1264297-99-5 C₂₀H₁₆BrN₃O₈ 
• 1631051-43-8 C₂₅H₂₀BrN₃O₇ 

Relevant academic research and scientific papers

Design, synthesis, and fungicidal activity of novel analogues of pyrrolnitrin

A series of novel analogues of pyrrolnitrin containing a thiophene moiety were designed and synthesized by a facile method, and their structures were characterized by 1H nuclear magnetic resonance (NMR) and high-resolution mass spectrometry. The isomers IV-h and V-h were isolated, and their structures were identified by 2D NMR, including heteronuclear multiple-quantum coherence (HMQC), heteronuclear multiple-bond correlation (HMBC), and nuclear Overhauser effect spectrometry (NOESY) spectra. Their fungicidal activities against five fungi were evaluated, and the results indicated that some of the title compounds showed excellent fungicidal activities in vitro against Alternaria solani, Gibberella zeae, Physalospora piricola, Fusarium omysporum, and Cercospora arachidicola at the dosage of 50 μg mL-1. Some compounds shown moderate activity at low dosage. Compound V-h could be considered as a leading structure for further design of agricultural fungicides.

Synthesis of 5- and 6-membered heterocycles by a strategy combining SNAr and SRN1 reactions

The SRN1 mechanism is compatible with many substituents on the benzenic substrate and allows SRN1 reactions to be combined with SNAr reactions in a strategy which brings together their corresponding synthetic advantages.Thus, compounds containing benzene fused to 5- or 6-membered heterocycles containing N (indoles), N and P (benzazaphospholes) and N and S (benzothiazines) are readily obtained. nucleophilic aromatic substitution / SRN1 / SNAr / benzene-fused heterocycles