400019-84-3

Upstream product

• 52813-63-5 (5R)-2,3,4,5-tetrahydro-5-hydroxymethyl-2-furanone 
• 262363-89-3 (3S,5R)-5-Hydroxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester 
• 214354-03-7 (3S,5S)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-benzyloxy-tetrahydro-pyridazine-1,2-dicarboxylic acid di-tert-butyl ester 
• 214354-11-7 (3S,5S)-5-Benzyloxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester 
• 214354-12-8 (3S,5S)-5-Acetoxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester 
• 214354-19-5 (3S,5S)-5-Hydroxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester 
• 400019-81-0 C₃₁H₄₄N₂O₇Si 
• 400019-88-7 C₁₆H₂₈N₂O₉S 
• 400019-83-2 (3S,5R)-5-Hydroxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 
• 400019-87-6 C₁₅H₂₆N₂O₇ 
• 128075-94-5 (R)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}dihydrofuran-2(3H)-one 
• 70-34-8 2,4-Dinitrofluorobenzene 

Downstream Products

• 31321-66-1 1-(2,4-dinitro-phenyl)-5-hydroxy-hexahydro-pyridazine-3-carboxylic acid 
• 24182-13-6 (3S,5S)-2-acetyl-1-(2,4-dinitrophenyl)-5-hydroxypiperazic acid 

Relevant academic research and scientific papers

Convenient synthesis of (3S,5S)-5-hydroxy- and (3R,5S)-5-chloropiperazic acids of a peptide antibiotic, monamycin G3

Convenient synthesis of (3S,5S)-5-hydroxy- and (3R,5S)-5-chloropiperazic acids, which are the important constituting moieties of an antibiotic monamycin G3, and their possible stereoisomers constructing of similar antibiotics was achieved from

Monamycin synthetic studies. Pt 1. An enantiospecific total synthesis of (3S,5S)-5-hydroxypiperazic acid from D-mannitol

The first enantiospecific total synthesis of (3S,5S)-hydroxypiperazic acid 1 is described. The synthesis begins from D-mannitol and exploits a tandem electrophilic hydrazination/nucleophilic cyclisation reaction to assemble the hexahydropyridazine ring system.