400031-65-4

Upstream product

• 132434-53-8 1-(4-bromophenyl)-3-(furan-2-yl)-2-propen-1-one 
• 328087-60-1 2-amino-6-(4-bromo-phenyl)-4-furan-2-yl-nicotinonitrile 

Downstream Products

• 400031-83-6 7-(4-bromo-phenyl)-5-furan-2-yl-3-(2-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Synthesis of some 2-thioxopyrido[2,3-d]pyrimidine ribofuranosides and their antimicrobial activity

2-Thioxo-3,5,7-trisubstituted-1-[2′,3′.5′-tri-O-benzoyl-β -D-ribofuranosyl]pyrido[2,3-d]pyri midin-4(IH)-ones have been prepared by the condensation of trimethylsilyl derivative of 2-thioxo-3,5,7-trisubstituted pyrido[2,3-d]pyrimidin-4(IH)-ones with β-D-ribofuranose 1-acetate-2,3,5-tribenzoate in 65%-78% yield. The structure of the synthesized ribofuranosides and their precursors have been established by IR. 1H NMR and elemental analysis. These derivatives have been screened for their antimicrobial activity.