400610-35-7Relevant academic research and scientific papers
2,3-Disubstituted acrylamides as potent glucokinase activators
Sidduri, Achyutharao,Grimsby, Joseph S.,Corbett, Wendy L.,Sarabu, Ramakanth,Grippo, Joseph F.,Lou, Jianping,Kester, Robert F.,Dvorozniak, Mark,Marcus, Linda,Spence, Cheryl,Racha, Jagdish K.,Moore, David J.
scheme or table, p. 5673 - 5676 (2010/11/17)
The phenylacetamide 1 represents the archtypical glucokinase activator (GKA) in which only the R-isomer is active. In order to probe whether the chiral center could be replaced, we prepared a series of olefins 2 and show in the present work that these com
Tetrazolyl-phenyl acetamide glucokinase activators
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, (2008/06/13)
Tetrazolyl-phenyl acetamides are active as glucokinase activators, and are able to increase insulin secretion, which makes them useful for treating type II diabetes.
Tetrazolyl-phenyl acetamide glucokinase activators
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Page column 22, (2010/01/31)
Tetrazolyl-phenyl acetamides are active as glucokinase activators, and are able to increase insulin secretion, which makes them useful for treating type II diabetes.
