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2-Dioxaborolan-2-yl)quinolin-2(1H)-one, also known as quinolin-2(1H)-one, is a heterocyclic chemical compound with the molecular formula C10H7BO2. It features a unique structure that includes both boron and oxygen atoms, making it a versatile building block in organic synthesis and pharmaceutical research. 2-dioxaborolan-2-yl)quinolin-2(1H)-one has garnered attention for its potential applications due to the biological and medicinal activities of its derivatives, which include antimicrobial, anti-inflammatory, and anticancer properties, as well as their potential as enzyme inhibitors and neuroprotective agents.

400620-72-6

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400620-72-6 Usage

Uses

Used in Pharmaceutical Research:
2-Dioxaborolan-2-yl)quinolin-2(1H)-one is used as a building block for the synthesis of functionalized quinolin-2(1H)-one derivatives, which exhibit a range of biological activities. These derivatives are valued for their potential applications in the development of new drugs targeting various diseases and conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Dioxaborolan-2-yl)quinolin-2(1H)-one serves as a key intermediate for the creation of a variety of complex organic molecules. Its unique structure allows for multiple synthetic pathways, facilitating the production of diverse chemical entities.
Used in Antimicrobial Applications:
The quinolin-2(1H)-one derivatives synthesized from 2-Dioxaborolan-2-yl)quinolin-2(1H)-one have demonstrated antimicrobial properties, making them useful as agents against bacterial and fungal infections. They are studied for their potential to combat drug-resistant strains and contribute to the development of new antimicrobial therapies.
Used in Anti-inflammatory Applications:
Due to their observed anti-inflammatory effects, quinolin-2(1H)-one derivatives are being explored for their use in treating inflammatory conditions. They may offer new treatment options for a variety of diseases characterized by chronic inflammation.
Used in Anticancer Applications:
The potential of quinolin-2(1H)-one derivatives as anticancer agents is being investigated, with studies focusing on their ability to inhibit the growth of cancer cells and their potential synergistic effects with existing chemotherapeutic drugs.
Used in Enzyme Inhibition:
2-Dioxaborolan-2-yl)quinolin-2(1H)-one derivatives have been studied for their capacity to inhibit specific enzymes, which is crucial in the regulation of various biological processes and could lead to treatments for enzyme-related diseases.
Used in Neuroprotection:
As neuroprotective agents, quinolin-2(1H)-one derivatives are being researched for their potential to protect neurons from damage or death, which could have implications for the treatment of neurodegenerative diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 400620-72-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,6,2 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 400620-72:
(8*4)+(7*0)+(6*0)+(5*6)+(4*2)+(3*0)+(2*7)+(1*2)=86
86 % 10 = 6
So 400620-72-6 is a valid CAS Registry Number.

400620-72-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1H-qu inolin-2-one

1.2 Other means of identification

Product number -
Other names 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:400620-72-6 SDS

400620-72-6Relevant academic research and scientific papers

Pd-Catalyzed Site-Selective Borylation of Simple Arenes via Thianthrenation?

Chen, Xiao-Yue,Huang, Yu-Hao,Zhou, Jian,Wang, Peng

, p. 1269 - 1272 (2020/08/13)

Site-selective borylation of simple arenes was realized in one pot via an electrophilic thianthrenation/Pd-catalyzed borylation sequence. The key to achieve this operatically simple process is the use of Pd catalysis, which could tolerate the solvent and acidic conditions used in the thianthrenation step. This protocol features mild conditions, broad functional group tolerance, and simple manipulations, and is suitable for late-stage functionalization of a wide range of pharmaceuticals and complex bioactive molecules.

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