400629-06-3

Basic information

• Product Name: 2-(TRIFLUOROMETHYL)PHENYL ACETATE
• Synonyms: 2-(TRIFLUOROMETHYL)PHENYL ACETATE;2-(TRIFLUOROMETHYL)PHENYL ACETATE, 97% MIN.;2-Acetoxybenzotrifluoride
• CAS NO: 400629-06-3
• Molecular Formula: C9H7F3O2
• Molecular Weight: 204.15
• Mol File: 400629-06-3.mol

Chemical Properties

• Boiling Point: 212.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.271±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(TRIFLUOROMETHYL)PHENYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(TRIFLUOROMETHYL)PHENYL ACETATE(400629-06-3)
• EPA Substance Registry System: 2-(TRIFLUOROMETHYL)PHENYL ACETATE(400629-06-3)

Safety Data

• Hazardous Substances Data: 400629-06-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(TRIFLUOROMETHYL)PHENYL ACETATE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of complex organic molecules with potential medicinal properties.
Used in Agrochemical Industry:
2-(TRIFLUOROMETHYL)PHENYL ACETATE is used as an intermediate in the synthesis of agrochemicals, playing a role in the creation of compounds that can be used in the development of pesticides and other agricultural products.
Used in Organic Compounds Synthesis:
2-(TRIFLUOROMETHYL)PHENYL ACETATE is used as a building block for the preparation of complex organic molecules in chemical research and development, facilitating the creation of new compounds with diverse applications.

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 98-08-8 α,α,α-trifluorotoluene 
• 108-24-7 acetic anhydride 
• 444-30-4 2-(trifluoromethyl)phenol 
• 33035-41-5 2-(diacetoxyiodo)mesitylene 

Downstream Products

• 115933-50-1 methyl 4-hydroxy-3-(trifluoromethyl)benzoate 

Relevant articles and documents

Ligand-Promoted Palladium-Catalyzed C?H Acetoxylation of Simple Arenes

The palladium-catalyzed C?H oxidation of simple arenes is an attractive strategy to obtain phenols, which have many applications in the fine chemicals industry. Although some advances have been made in this research area, low reactivity and selectivity are, in general, observed. This report describes a new catalytic system for the efficient C?H acetoxylation of simple arenes based on Pd(OAc)2 and a pyridinecarboxylic acid ligand.

Steric control of site selectivity in the Pd-catalyzed C-H acetoxylation of simple arenes

This report describes the use of an oxidant and a ligand to control site selectivity in the Pd(OAc)2-catalyzed C-H acetoxylation of simple arenes. The use of MesI(OAc)2 as the terminal oxidant in combination with acridine as the ligand results in primarily sterically controlled selectivity. In contrast, with Pd(OAc)2 as the catalyst and PhI(OAc)2 as the oxidant, electronic effects dominate the selectivity of arene C-H acetoxylation.

NOVEL PHENOL DERIVATIVE

Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt t

Remarkably high reactivity of Pd(OAc)2/pyridine catalysts: Nondirected C-H oxygenation of arenes

Less is more: The rational optimization and general applicability of the catalytic system Pd(OAc)2/pyridine is described (see scheme). The catalyst shows excellent reactivity in the C-H oxygenation of simple aromatic substrates. The Pd/pyridine ratio is critical as the use of one equivalent of pyridine per Pd center leads to dramatic enhancements in both reactivity and site selectivity in comparison to Pd(OAc)2 alone.

Platinum and palladium complexes containing cationic ligands as catalysts for arene H/D exchange and oxidation

Cationic catalysts in HD: Palladium(II) and platinum(II) complexes of pyridinium-substituted bipyridine ligands are highly active and stable catalysts for H/D exchange and oxidation of aromatic C-H bonds (TONs up to 3200, TOFs up to 0.1 s-1; se