40067-82-1

Basic information

• Product Name: N'-HYDROXY-3-METHYLBENZENECARBOXIMIDAMIDE
• Synonyms: BUTTPARK 33\11-53;N'-HYDROXY-3-METHYLBENZENECARBOXIMIDAMIDE;Benzenecarboximidamide, N-hydroxy-3-methyl- (9CI);N'-Hydroxy-3-methylbenzenecarboximideamide;N'-Hydroxy-3-methylbenzenecarboximidamide, N'-Hydroxy-3-methylbenzamidine;(E)-3-Hydroxy-2-(quinolin-2-yl)acrylaldehyde;N-hydroxy-3-methylbenzimidamide
• CAS NO: 40067-82-1
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Product Categories: OXIME;AMIDINE;Nitrogen Compounds;Organic Building Blocks;Oximes
• Mol File: 40067-82-1.mol
• Article Data: 46

Chemical Properties

• Melting Point: 82-87 °C(lit.)
• Boiling Point: 329.5 °C at 760 mmHg
• Flash Point: 153.1 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 7.13E-05mmHg at 25°C
• Refractive Index: 1.564
• PKA: 7.04±0.69(Predicted)
• CAS DataBase Reference: N'-HYDROXY-3-METHYLBENZENECARBOXIMIDAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N'-HYDROXY-3-METHYLBENZENECARBOXIMIDAMIDE(40067-82-1)
• EPA Substance Registry System: N'-HYDROXY-3-METHYLBENZENECARBOXIMIDAMIDE(40067-82-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 40067-82-1(Hazardous Substances Data)

Usage

Uses

N''-Hydroxy-3-methylbenzenecarboximidamide

InChI:InChI=1/C8H10N2O/c1-6-3-2-4-7(5-6)8(9)10-11/h2-5,11H,1H3,(H2,9,10)

Upstream product

• 620-22-4 3-Methylbenzonitrile 
• 2362-63-2 3-methylthiobenzamide 
• 620-23-5 m-tolyl aldehyde 
• 52707-50-3 3-methylbenzaldehyde oxime 

Downstream Products

• 16013-05-1 3-m-tolyl-[1,2,4]oxadiazole 
• 132198-48-2 3-m-Tolyl-1-oxa-2,4-diaza-spiro[4.5]dec-2-ene 
• 94538-44-0 3-(3-toluyl)-5-(3-toluyl)-1,2,4-oxadiazole 
• 87944-75-0 5-Methyl-3-(m-tolyl)-1,2,4-oxadiazole 
• 88303-27-9 C₁₀H₁₂N₂O₂ 
• 111249-50-4 3-(3-methylphenyl)-5-phenyl-1,2,4-oxadiazole 
• 94192-16-2 3-<(3-m-Tolyl)-1,2,4-oxadiazol-5-yl>propionic acid 
• 50737-31-0 5-(chloromethyl)-3-(m-tolyl)-1,2,4-oxadiazole 
• 851167-17-4 4-(3-m-tolyl-1,2,4-oxadiazol-5-yl)-butan-2-one 
• 1040725-83-4 3-(3-methylphenyl)-1,2,4-oxadiazolyl methyl-3'-phenyl-spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)dione 
• 1040725-86-7 3-(3-methylphenyl)-1,2,4-oxadiazolyl methyl-3'-(4-methoxyphenyl)-spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)dione 
• 138528-21-9 5,5'-(1,2-ethanediyl)-bis<3-(m-tolyl)-1,2,4-oxadiazole> 
• 1259061-56-7 5-hydroxymethyl-3-(m-tolyl)-1,2,4-oxadiazole 

Relevant articles and documents

Synthesis and Biological Screening of Novel 5-(5-Aryl-1-phenyl-1H-pyrazol-3-yl)-3-aryl-1,2,4-oxadiazole Derivatives

A new series of 5-(5-aryl-1-phenyl-1H-pyrazol-3-yl)-3-aryl-1,2,4-oxadiazole (6a-o) have been synthesized by a cyclocondensation reaction of ethyl 5-(4-chlorophenyl)-1-phenyl-1H-pyrazole-3-carboxylate (3a-c) with aryl imidoxime (5a-e). The newly synthesize

Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-containing pyrazolo[3,4-b]pyridinones as a new series of AMPKɑ1β1γ1 activators

Adenosine monophosphate-activated protein kinase (AMPK) plays a key role in maintaining whole-body homeostasis and has been regarded as a therapeutic target for the treatment of diabetic nephropathy (DN). Herein, a series of 1,2,4-oxadiazole-containing py

SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)

A simple, mild and practical cascade process for the direct conversion of aldehydes to cyanamides was developed featuring a wide substrate scope and great functional group tolerability. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable cyanamides in a pot, atom, and step-economical manner with a green nitrogen source. This protocol will serve as a robust tool for the installation of the cyanamide moiety in various complicated molecules.