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(6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester is a versatile chemical compound that serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Derived from 6-amino-pyridin-3-ylmethyl, this tert-butyl ester of carbamic acid is known for its ability to modify the activity of enzymes and receptors in biological systems, making it a valuable building block for the synthesis of heterocyclic compounds in the pharmaceutical industry. Its applications extend to the development of new materials and the field of organic chemistry.

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  • 400720-77-6 Structure
  • Basic information

    1. Product Name: (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester
    2. Synonyms: (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester;tert-butyl ((6-aMinopyridin-3-yl)Methyl)carbaMate
    3. CAS NO:400720-77-6
    4. Molecular Formula: C11H17N3O2
    5. Molecular Weight: 223.27158
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 400720-77-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 401.6±35.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.138±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. PKA: 11.58±0.46(Predicted)
    10. CAS DataBase Reference: (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester(400720-77-6)
    12. EPA Substance Registry System: (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester(400720-77-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 400720-77-6(Hazardous Substances Data)

400720-77-6 Usage

Uses

Used in Pharmaceutical Industry:
(6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester is used as a key intermediate for the synthesis of various drugs, leveraging its capacity to modify enzyme and receptor activities in biological systems. This contributes to the development of new therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester is utilized as a precursor in the production of agricultural chemicals, enhancing the effectiveness of these compounds in managing pests and diseases while minimizing environmental impact.
Used in Organic Chemistry Research:
(6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester is employed as a building block in the synthesis of heterocyclic compounds, which are widely used in the pharmaceutical industry. Its applications in organic chemistry research facilitate the discovery and development of novel chemical entities with potential applications in various fields.
Used in Material Science:
(6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester also finds applications in the development of new materials, where its unique properties can be harnessed to create innovative solutions in areas such as nanotechnology, polymer science, and advanced materials for various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 400720-77-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,7,2 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 400720-77:
(8*4)+(7*0)+(6*0)+(5*7)+(4*2)+(3*0)+(2*7)+(1*7)=96
96 % 10 = 6
So 400720-77-6 is a valid CAS Registry Number.

400720-77-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-[(6-aminopyridin-3-yl)methyl]carbamate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:400720-77-6 SDS

400720-77-6Relevant articles and documents

METTL3 INHIBITORY COMPOUNDS

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Paragraph 00983; 00987-00989, (2020/10/20)

The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity: X-Y-Z5 (I) wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity 10 is implicated.

NOVEL HETEROCYCLIC COMPOUNDS AS INHIBITORS OF VANIN-1 ENZYME

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Page/Page column 108; 109, (2016/12/22)

Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

AMINOPYRIDINE DERIVATIVES

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Page/Page column 74, (2009/12/05)

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (such as asthma or COPD); and methods of treating patients with such compounds; wherein R1 - R11 ar

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