400727-04-0

Basic information

• Product Name: 1-(2-pyridinyl)-Cyclopentanecarbonitrile
• Synonyms: 1-(2-pyridinyl)-Cyclopentanecarbonitrile;Cyclopentanecarbonitrile, 1-(2-pyridinyl)-
• CAS NO: 400727-04-0
• Molecular Formula: C11H12N2
• Molecular Weight: 172.22638
• Mol File: 400727-04-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 334.051°C at 760 mmHg
• Flash Point: 118.048°C
• Appearance: /
• Density: 1.097g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.553
• PKA: 5.65±0.19(Predicted)
• CAS DataBase Reference: 1-(2-pyridinyl)-Cyclopentanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-pyridinyl)-Cyclopentanecarbonitrile(400727-04-0)
• EPA Substance Registry System: 1-(2-pyridinyl)-Cyclopentanecarbonitrile(400727-04-0)

Safety Data

• Hazardous Substances Data: 400727-04-0(Hazardous Substances Data)

Usage

General Description

1-(2-pyridinyl)-Cyclopentanecarbonitrile is a chemical compound with the molecular formula C12H11N. It is a member of the pyridine family and is commonly used in organic synthesis and pharmaceutical research. 1-(2-pyridinyl)-Cyclopentanecarbonitrile is known for its ability to function as a versatile building block in the synthesis of various biologically active molecules, including potential drugs and pharmaceuticals. Its unique structural and chemical properties make it valuable for developing new compounds with potential therapeutic applications in areas such as oncology, neuroscience, and infectious diseases. Additionally, 1-(2-pyridinyl)-Cyclopentanecarbonitrile is also used as an intermediate in the production of agrochemicals and specialty chemicals.

InChI:InChI=1/C11H12N2/c12-9-11(6-2-3-7-11)10-5-1-4-8-13-10/h1,4-5,8H,2-3,6-7H2

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 2739-97-1 pyridine-2-acetonitrile 

Downstream Products

• 1616925-60-0 5-benzyloxy-6-hydroxy-2-(1-pyridin-2-ylcyclopentylmethyl)pyrimidine-4-carboxylic acid [2-(tert-butyldimethylsilanyloxy)ethyl]isopropylamide 
• 1616925-59-7 5-benzyloxy-6-hydroxy-2-(1-pyridin-2-ylcyclopentylmethyl)pyrimidine-4-carboxylic acid 
• 1616925-58-6 5-benzyloxy-6-hydroxy-2-(1-pyridin-2-ylcyclopentylmethyl)pyrimidine-4-carboxylic acid tert-butyl ester 

Relevant articles and documents

Amide compound and derivative thereof, preparation method, pharmaceutical composition and application thereof

The invention discloses an amide compound and derivative thereof, a preparation method, a pharmaceutical composition and application thereof. The structure of the amide compound is shown as a formula (I). The derivatives of theamide compound relate to a stereoisomer, a tautomer, a metabolite, a metabolic precursor, a prodrug, a solvate, a salt of the solvate, a crystal, a pharmaceutically acceptable salt or a mixture of the above of theamide compound. The amide compound and the derivative thereof have an efficient inhibition effect on indoleamine 2, 3-dioxygenase 1, and can be used for preparing medicines for treating indoleamine 2, 3-dioxygenase 1 mediated immunosuppression related diseases, the prepared medicine can exert the medicine effect at the molecular level and is wide in application, and the synthesis method of the compound is simple, convenient and easy to operate.

PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE

The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.