4008-46-2

Basic information

• Product Name: Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate
• Synonyms: 4-Hydroxy-8-Methoxy-quinoline-2-carboxylic acid Methyl ester;Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate
• CAS NO: 4008-46-2
• Molecular Formula: C₁₂H₁₁NO₄
• Molecular Weight: 233.22
• Mol File: 4008-46-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 159-160 °C
• Boiling Point: 445.0±40.0 °C(Predicted)
• Appearance: /
• Density: 1.316
• PKA: 6.85±0.40(Predicted)
• CAS DataBase Reference: Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate(4008-46-2)
• EPA Substance Registry System: Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate(4008-46-2)

Safety Data

• Hazardous Substances Data: 4008-46-2(Hazardous Substances Data)

Usage

General Description

Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate is a chemical compound with the molecular formula C13H11NO4. It is a derivative of quinoline and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate has been found to exhibit antioxidant, antimicrobial, and antiviral properties, making it potentially valuable for a wide range of applications. Its structure includes a quinoline ring with a hydroxy and methoxy group at specific positions, as well as a carboxylic acid ester group. Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate is known for its yellow to orange color and is typically handled and stored in a dry, cool, and well-ventilated area.

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Downstream Products

• 21638-90-4 methyl 8-hydroxyquinoline-2-carboxylate 
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Relevant articles and documents

TiO2 modified with a Ru(ii)-N′NN′ 8-hydroxyquinolyl complex for efficient gaseous photoreduction of CO2

A new rigid neutral Ru(ii) pincer complex [Ru(N′NN′)(ONO)] was synthesized from cationic [Ru(N′NN′)(MeCN)2Cl]Cl (N′NN′, 2,6-bis(N-benzyl-benzimidazol-2-yl)pyridine) and 4,8-dihydroxyquiniline-2-carboxylic acid (ONO). The X-ray diffraction analysis indicates that the Ru(ii) center adopts a slightly distorted octahedral geometry, in which the two benzyl moieties of the N′NN′ ligand are located on the same side of the coordination plane, defined by three N atoms of N′NN′ and the Ru(ii) center, and the dihedral angles of the benzyl group and the Ru(ii)-N′NN′ plane are 89.1° and 74.9°, respectively. Upon loading onto TiO2 nanoparticles (P25), this Ru(ii) complex exhibits an efficient CO2 photoreduction ability with CO/CH4 production activities of 26.6/17.2 μmol g-1 h-1 in a gaseous photocatalytic system containing CO2 and H2O vapor, which is much better than that of the pristine TiO2 nanoparticles. This result gives a good example of TiO2 nanoparticles loaded with the Ru(ii) pincer complex acting as a heterogeneous photocatalytic CO2 reduction system, which could facilitate the development of a more feasible artificial photosynthesis system.

HEPATITIS C INHIBITOR COMPOUNDS

Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.

Platelet adenosine diphosphate receptor antagonists

Compounds of the following formula (I): where a, b, R1, R2, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, met