7101-82-8

Basic information

• Product Name: 2-Butenedioic acid, 2-[(2-Methoxyphenyl)aMino]-, 1,4-diMethyl ester
• Synonyms: 2-Butenedioic acid, 2-[(2-Methoxyphenyl)aMino]-, 1,4-diMethyl ester;o-anisidino-butenedioic acid dimethyl ester
• CAS NO: 7101-82-8
• Molecular Formula: C₁₃H₁₅NO₅
• Molecular Weight: 265.2619
• Mol File: 7101-82-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Butenedioic acid, 2-[(2-Methoxyphenyl)aMino]-, 1,4-diMethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenedioic acid, 2-[(2-Methoxyphenyl)aMino]-, 1,4-diMethyl ester(7101-82-8)
• EPA Substance Registry System: 2-Butenedioic acid, 2-[(2-Methoxyphenyl)aMino]-, 1,4-diMethyl ester(7101-82-8)

Safety Data

• Hazardous Substances Data: 7101-82-8(Hazardous Substances Data)

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 25007-54-9 Dimethyl 2-oxosuccinate 
• 553-90-2 Dimethyl oxalate 

Downstream Products

• 7101-90-8 8-methoxy-quinolin-4(1H)-one-2-carboxylic acid methyl ester 
• 59-00-7 xanthurenic acid 
• 21638-90-4 methyl 8-hydroxyquinoline-2-carboxylate 
• 1571-30-8 8-hydroxy-quinoline-2-carboxylic acid 
• 4008-46-2 methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate 

Relevant articles and documents

Copper-Catalyzed Three-Component Cascade Michael Addition/Heck-Type Alkylation/Annulation: Accessing Fully Substituted 1,3-Dihydro-2 H-pyrrol-2-ones

We report a highly efficient copper-catalyzed three-component reaction of alkylamines, acetylenedicarboxylates, and α-bromocarbonyls for the assembly of fully substituted 1,3-dihydro-2H-pyrrol-2-ones. A variety of alkylamines and ammonium salt are functionalized with acetylenedicarboxylates and α-bromocarbonyls. N-aryl enaminoesters are also successfully alkylated with α-bromocarbonyls. This protocol is understood to proceed through radical Heck-type coupling of in-situ-generated bulky trisubstituted alkenes with bulky tertiary alkyl bromides, which is realized for the first time.

Microwave-assisted preparation of quinolone and quinoline derivatives

Quinolinone derivatives can be obtained in microwave-assisted syntheses by reaction of aniline derivatives with acetylene dicarboxylic esters, a malonic acid diester or -keto ester derivatives. The reaction proceeds under mild conditions in short reaction