400801-82-3

Basic information

• Product Name: Tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate
• Synonyms: Tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate
• CAS NO: 400801-82-3
• Molecular Formula: C17H21N3O2
• Molecular Weight: 299.36754
• Mol File: 400801-82-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate(400801-82-3)
• EPA Substance Registry System: Tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate(400801-82-3)

Safety Data

• Hazardous Substances Data: 400801-82-3(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate is a chemical compound with the formula C18H20N4O2. It is a dihydropyridine derivative with a pyrrolopyridine group, and it is commonly used as a building block in the synthesis of pharmaceutical compounds. This chemical has potential biological activity and may be used in drug discovery and development. However, it should be handled with care due to its potential health hazards, and proper safety precautions should be taken when working with this compound.

Upstream product

• 271-63-6 7-Azaindole 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Downstream Products

• 1342949-34-1 N-(3,4-difluorophenyl)-3-(piperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-6-amine 
• 1342812-95-6 tert-butyl 4-(6-((3,4-difluorophenyl)amino)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylate 

Relevant articles and documents

7-azaindole heterocyclic compound and preparation method and application thereof

The invention belongs to the technical field of 7-azaindole heterocyclic compounds, and discloses a 7-azaindole heterocyclic compound and a preparation method and application thereof. The structure of the compound is shown as a general formula I, a general formula II, a general formula III or a general formula IV (detailed description). The compound can simultaneously have a good effect of inhibiting central nervous excitation on cell and mouse excitation models, and the compound has relatively low neurotoxicity.

Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-Like Proteins

The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and of diseases or conditions associated with amyloid-like proteins. The compounds of the present invention can also be used in the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system. The present invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the preparation of medicaments for treating or preventing diseases or conditions associated with amyloid and/or amyloid-like proteins. A method of treating or preventing diseases or conditions associated with amyloid and/or amyloid-like proteins is also disclosed.

Pyrazole-based cathepsin S inhibitors with improved cellular potency

High potency pyrazole-based noncovalent inhibitors of human cathepsin S (CatS) were developed by modification of the benzo-fused 5-membered ring heterocycles found in earlier series of CatS inhibitors. Although substitutions on this heterocyclic framework