400858-77-7Relevant academic research and scientific papers
Conversion of aldimines to secondary amines using iron-catalysed hydrosilylation
Saini, Anu,Smith, Cecilia R.,Wekesa, Francis S.,Helms, Amanda K.,Findlater, Michael
supporting information, p. 9368 - 9372 (2019/01/03)
Iron-catalyzed hydrosilylation of imines to amines using a well-defined iron complex is reported. This method employs relatively mild conditions, by reaction of imine, (EtO)3SiH in a 1 : 2 ratio in the presence of 1 mol% precatalyst ([BIAN]Fe(η6-toluene), 3, BIAN = bis(2,6-diisopropylaniline)acenaphthene) at 70 °C. A broad scope of imines was readily converted into the corresponding secondary amines without the need for precatalyst activators.
