40088-59-3

Basic information

• Product Name: 2-(tert-butyl)-6-(tert-butylamino)cyclohexa-2,5-diene-1,4-dione
• CAS NO: 40088-59-3
• Molecular Weight: 235.326
• Mol File: 40088-59-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(tert-butyl)-6-(tert-butylamino)cyclohexa-2,5-diene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(tert-butyl)-6-(tert-butylamino)cyclohexa-2,5-diene-1,4-dione(40088-59-3)
• EPA Substance Registry System: 2-(tert-butyl)-6-(tert-butylamino)cyclohexa-2,5-diene-1,4-dione(40088-59-3)

Safety Data

• Hazardous Substances Data: 40088-59-3(Hazardous Substances Data)

Upstream product

• 3602-55-9 2-tert-butyl-1,4-benzoquinone 
• 75-64-9 tert-butylamine 

Relevant articles and documents

A Catalytic Oxidative Quinone Heterofunctionalization Method: Synthesis of Strongylophorine-26

The preparation of heteroatom-substituted p-quinones is ideally performed by direct addition of a nucleophile followed by in situ reoxidation. Albeit an appealing strategy, the reactivity of the p-quinone moiety is not easily tamed and no broadly applicable method for heteroatom functionalization exists. Shown herein is that Co(OAc)2 and Mn(OAc)3?2 H2O act as powerful catalysts for oxidative p-quinone functionalization with a collection of O, N, and S nucleophiles, using oxygen as the terminal oxidant. Preliminary mechanistic observations and the first synthesis of the cytotoxic natural product strongylophorine-26 is presented.