400888-63-3

Upstream product

• 708-54-3 3-methyl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-5-one 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1233390-60-7 C₂₆H₂₅NOS 
• 1141-88-4 2-Aminophenyl disulfide 
• 753487-11-5 4-(4-methoxy-phenyl)-10-methyl-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel tetracyclic benzothiazepines

6-Arylidene-2,3-dimethyl-6,7,8,9-tetrahydro-benzocyclohepten-5-one 2a-l were obtained by the condensation of 2,3-dimethyl/3-methyl benzocyclohepten-5- one 1 with appropriate aromatic aldehydes, and upon condensation with 2-aminothiophenol in ethyl alcohol yielded 1,5-benzothiazepine derivatives 3a-l, respectively. Compounds 3d and 3h were found to possess antimicrobial activity when tested against B. Subtilis. Compounds 3i and 3j were found to possess moderate anti-inflammatory activity. Compound 3b was found to possess comparable antifungal activity when compared to clotrimazole against Trichomonas species. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

Synthesis and characterization of new isoxazoles derived from benzosuberones

6-Arylidene-3-methyl-6,7,8,9-tetrahydro-5H-bezo[a]cyclo-hepten-5-ones 2a-g, are obtained by the condensation of 3-methyl benzocyclohepten-5-one 1 with appropriate aromatic aldehydes on reaction with hydroxylamine hydrochloride in alkaline medium to give 9

Synthesis and antimicrobial activity of new thiazolo/thiazinopyrimidino[6,5-c]benzocycloheptenes

Synthesis of 2-methyl-8-phenyl-5,6,7,8,10,11-hexahydrobenzo[6,7]- cyclohepta[d][1,3]thiazolo[3,2-a]pyrimidin-10-ones (4a-g), 2-methyl-8-phenyl- 5,6,7,8; 11,12-hexahydro-10H-benzo[6',7']cyclohepta[4,5]pyrimido[2,1-b][1,3]- thiazin-10-ones (6a-g) and 2,11-dimethyl-8-phenyl-5,6,7,8,10,11- hexahydrobenzo-[6,7]cyclohepta[d][1,3]thiazolo[3,2-a]pyrimidin-10-ones (8a-g) have been described. A number of compounds show promising antimicrobial acitity.