40096-23-9 Usage
Description
3-Fluorothioanisole, with the chemical formula C7H7FS, is a colorless liquid characterized by a pungent odor. It serves as a fundamental building block in organic synthesis and is renowned for its versatility in chemical reactions, such as nucleophilic aromatic substitutions. Its role as a precursor to other fluorinated compounds and its unique properties render it an indispensable tool in the pharmaceutical and agrochemical industries for the synthesis of a wide array of organic molecules.
Uses
Used in Pharmaceutical Industry:
3-Fluorothioanisole is utilized as a reagent in the synthesis of various pharmaceutical compounds due to its ability to participate in nucleophilic aromatic substitutions and its potential to form other fluorinated compounds. This makes it a valuable asset in the development of new drugs and medicinal agents.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Fluorothioanisole is employed as a precursor for the creation of fluorinated agrochemicals, which can enhance the effectiveness of pesticides and other agricultural chemicals, thereby contributing to more efficient crop protection.
Used in Fragrance and Flavoring Industry:
3-Fluorothioanisole is also used as a component in the production of fragrances and flavoring agents, capitalizing on its distinctive aromatic properties to create unique scents and tastes for a variety of consumer products.
Check Digit Verification of cas no
The CAS Registry Mumber 40096-23-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,9 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 40096-23:
(7*4)+(6*0)+(5*0)+(4*9)+(3*6)+(2*2)+(1*3)=89
89 % 10 = 9
So 40096-23-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H7FS/c1-9-7-4-2-3-6(8)5-7/h2-5H,1H3
40096-23-9Relevant articles and documents
Synthesis and Biological Activity of trans-(+/-)-N-Methyl-2-(3-pirydyl)-2-tetrahydrothiopyrancarbothioamide 1-Oxide (RP 49356) and Analogues: A New Class of Potassium Channel Opener
Brown, Thomas J.,Chapman, Robert F.,Cook, David C.,Hart, Terance W.,McLay, Iain M.,et al.
, p. 3613 - 3624 (2007/10/02)
The synthesis and biological activity of trans-(+/-)-N-methyl-2-(3-pyridyl)-2-tetrahydrothiopyrancarbothioamide 1-oxide (8a, RP 49356) and analoques is reported.These compounds constitute a new structural class of K+-channel opener.The effects of changes in the pyridyl group, thioamide, and thiane ring on in vitro K+-channel opening activity are discussed.A 3-pyridyl or 3-quinolyl group, a small N-alkyl thioamide function, and a thiane oxide ring, in which the sulfoxide is in a trans relationship to thioamide, are preferred for activity.Selected compounds were tested intravenously in the normotensive anaesthetized rat for hypotensive effects, and the activities reflect their in vitro K+-channel opening activity.This led to further evaluation of compound 8a and the selection of the (-)-enantiomer 8b (RP 52891) for development as an antihypertensive and antianginal agent.
