Welcome to LookChem.com Sign In|Join Free
  • or
Ethyl (Z)-2-acetamido-3-(4-fluorophenyl)acrylate is a chemical compound with the molecular formula C13H12FNO3. It is an organic molecule that belongs to the class of acrylates, which are esters derived from acrylic acid. This specific compound features a (Z)-configuration, indicating the geometric arrangement of its double bond, with the acetamido group (-CONH2) and a 4-fluorophenyl group attached to the acrylate backbone. The presence of the fluorine atom in the phenyl ring imparts unique electronic and steric properties to the molecule, which can be significant in various chemical reactions and applications. Ethyl (Z)-2-acetamido-3-(4-fluorophenyl)acrylate is used in the synthesis of pharmaceuticals and other specialty chemicals, where its reactivity and structural features are leveraged to create complex molecular architectures.

401-12-7

Post Buying Request

401-12-7 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

401-12-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 401-12-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 401-12:
(5*4)+(4*0)+(3*1)+(2*1)+(1*2)=27
27 % 10 = 7
So 401-12-7 is a valid CAS Registry Number.

401-12-7Relevant academic research and scientific papers

Synthesis of Indole-2-carboxylate Derivatives via Palladium-Catalyzed Aerobic Amination of Aryl C-H Bonds

Clagg, Kyle,Hou, Haiyun,Weinstein, Adam B.,Russell, David,Stahl, Shannon S.,Koenig, Stefan G.

supporting information, p. 3586 - 3589 (2016/08/16)

A direct oxidative C-H amination affording 1-acetyl indolecarboxylates starting from 2-acetamido-3-arylacrylates has been achieved. Indole-2-carboxylates can be targeted with a straightforward deacetylation of the initial reaction products. The C-H amination reaction is carried out using a catalytic Pd(II) source with oxygen as the terminal oxidant. The scope and application of this chemistry is demonstrated with good to high yields for numerous electron-rich and electron-poor substrates. Further reaction of selected products via Suzuki arylation and deacetylation provides access to highly functionalized indole structures.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 401-12-7