40107-67-3Relevant academic research and scientific papers
P(RNCH2CH2)3N-catalyzed diastereoselective synthesis of oxazolines
Kisanga, Philip,Ilankumaran, Palanichamy,Verkade, John G
, p. 6263 - 6266 (2001)
We report herein that the strong nonionic bases P(RNCH2CH2)3N(R = Me, 1a; i-Pr, 1b) catalyze the diastereoselective synthesis of thirteen oxazolines in the presence of 5-30% of these catalysts. The formation of the oxazolines proceeds under very mild conditions in good to excellent yields with high diastereoselectivity (>95:5) for the trans isomer.
