40110-98-3

Basic information

• Product Name: 1-O-(6-Amino-9H-purin-9-yl)-2,3-anhydro-β-D-lyxofuranose
• Synonyms: 1-O-(6-Amino-9H-purin-9-yl)-2,3-anhydro-β-D-lyxofuranose
• CAS NO: 40110-98-3
• Molecular Formula: C₁₀H₁₁N₅O₃
• Molecular Weight: 249.22604
• Mol File: 40110-98-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 591.4°C at 760 mmHg
• Flash Point: 311.5°C
• Appearance: /
• Density: 2.23g/cm³
• Vapor Pressure: 7.8E-15mmHg at 25°C
• Refractive Index: 2.035
• CAS DataBase Reference: 1-O-(6-Amino-9H-purin-9-yl)-2,3-anhydro-β-D-lyxofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-(6-Amino-9H-purin-9-yl)-2,3-anhydro-β-D-lyxofuranose(40110-98-3)
• EPA Substance Registry System: 1-O-(6-Amino-9H-purin-9-yl)-2,3-anhydro-β-D-lyxofuranose(40110-98-3)

Safety Data

• Hazardous Substances Data: 40110-98-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11N5O3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(18-7)4(1-16)17-10/h2-4,6-7,10,16H,1H2,(H2,11,12,13)/t4-,6+,7+,10-/m1/s1

Upstream product

• 58-61-7 adenosine 
• 5536-17-4 arabinosyl adenine 

Downstream Products

• 102997-84-2 6-N-5'-O-Bis<4-methoxytriphenylmethyl>-2',3'-lyxo-anhydroadenosine 
• 29411-70-9 9-(3′-azido-3′-deoxy-β-D-arabinofuranosyl)purine 
• 6998-75-0 3'-deoxydenosine 
• 13276-53-4 9-(2'-deoxy-β-D-threo-ribofuranosyl)-adenine 
• 102997-86-4 6-N-(4-Methoxytriphenylmethyl)-9-<5'-O-(4-methoxytriphenylmethyl)-2'-deoxy-β-D-threo-pentofuranosyl>-adenine 
• 102997-88-6 6-N-(4-Methoxytriphenylmethyl)-9-<5'-O-(4-methoxytriphenylmethyl)-2'-deoxy-2'-(R)-deuterio-3'-(R)-β-D-pentofuranosyl>-adenine 
• 102997-85-3 6-N-(4-Methoxytriphenylmethyl)-9-<5'-O-(4-methoxytriphenylmethyl)-3'-deoxy-β-D-threo-pentofuranosyl>-adenine 
• 102997-87-5 6-N-(4-Methoxytriphenylmethyl)-9-<5'-O-(4-methoxytriphenylmethyl)-2'-(S)-3'-(S)-deuterio-3'-deoxy-β-D-pentofuranosyl>-adenine 
• 73-03-0 cordycepin 

Relevant articles and documents

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Studies on biologically active nucleosides and nucleotides. 3. Synthesis of 9-(3-bromo-3-deoxy-2,5-di-O-acetyl-β-D-xylofuranosyl)adenine

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MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE IN TAUOPATHIES

Oligonucleotides comprising modifications at the 2' and/or 3' positions(s) along with methods of 5 making and use against Alzheimer disease and other tauopathies are disclosed.

NEW 2' AND/OR 5' AMINO-ACID ESTER PHOSPHORAMIDATE 3'-DEOXY ADENOSINE DERIVATIVES AS ANTI-CANCER COMPOUNDS

The present invention relates to chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours inhomo sapiens. The compounds are derivatives of cordycepin (3'-deoxyadenosine) having a 2' and/or 5'- amino-acid ester phosphoramidate moeity.