40125-55-1Relevant academic research and scientific papers
Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X
-
Page/Page column 162, (2014/09/03)
The present invention relates to compounds derived from sugars which reproduce the epitopes of Shigella flexneri serotypes 3a and X and to the use thereof for the preparation of vaccine compositions. More specifically, the subject matter of the present in
GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3A AND X
-
, (2010/10/03)
The present invention relates to compounds derived from sugars which reproduce the epitopes of Shigella flexneri serotypes 3a and X and to the use thereof for the preparation of vaccine compositions. More specifically, the subject matter of the present invention relates to novel glycoconjugated compounds comprising oligosaccharides or polysaccharides described hereinafter, to the method for synthesizing these oligosaccharides or polysaccharides and glycoconjugates, to derivatives of these oligosaccharides or polysaccharides, to compositions containing same, and also to the use of the glycoconjugates for vaccination purposes. Finally, the present invention relates to methods for diagnosing a Shigella flexneri infection using one or more oligosaccharides or polysaccharides or conjugates thereof.
Radicals from aldehydes: A convergent access to dienes and δ-lactones
Bagal, Sharanjeet K.,Tournier, Lucie,Zard, Samir Z.
, p. 1485 - 1490 (2007/10/03)
A convenient method for the generation of O,S-acetal xanthates from aldehydes has been developed. The corresponding nucleophilic radicals undergo facile addition to unactivated olefins and the resulting adducts can be further elaborated to generate dienes
