40137-51-7Relevant academic research and scientific papers
Hydroxamic Acids as Chemoselective (ortho-Amino)arylation Reagents via Sigmatropic Rearrangement
Shaaban, Saad,Tona, Veronica,Peng, Bo,Maulide, Nuno
supporting information, p. 10938 - 10941 (2017/08/30)
The use of readily available hydroxamic acids as reagents for the chemoselective (ortho-amino)arylation of amides is described. This reaction proceeds under metal-free, mild conditions, displays a very broad scope, and constitutes a direct approach for the metal-free attachment of aniline residues to carbonyl derivatives.
Reactions of hydroxylamines with ethyl cyanoformate. Preparation of aminonitrones and their synthetic applications
Branco,Prabhakar,Lobo,Williams
, p. 6335 - 6360 (2007/10/02)
The reaction of hydroxylamines with ethyl cyanoformate 1 leads to the formation of carbethoxyamino nitrones. 2. UV spectroscopy provided information that suggested the nitrone structure for these compounds in solution. X-ray analysis of 2a confirmed that it exists entirely in the nitrone form in the solid state. These nitrones are shown to be excellent starting materials for a variety of nitrogen containing compounds, namely, imidazoles, benzimidazoles, benzimidazolones, oxadiazolones, N-arylamidines and quinoxalone.
