401610-08-0Relevant academic research and scientific papers
The catalytic aerobic synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds
Gu, Lijun,Jin, Cheng,Zhang, Hongtao
supporting information, p. 1579 - 1582 (2015/03/18)
A highly efficient Cu-catalyzed direct hydroxylation of phosphonate compounds has been developed. This transformation provides a powerful method for the synthesis of quaternary α-hydroxy phosphonates in good yields. The direct transformation process, regiospecific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.
Synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds
Liu, Jiyan,Wang, Wei,Wang, Rui,Gu, Lijun
supporting information, p. 559 - 562 (2015/05/27)
It was found for the first time that Cs2CO3 serves as highly efficient catalyst for the direct hydroxylation reactions of phosphonates under mild conditions. This reaction provides an efficient approach to quaternary α-hydroxy phosph
C-H hydroxylation of phosphonates with oxygen in [bmIm]OH to produce quaternary α-hydroxy phosphonates
Li, Xiangguang,Jin, Cheng,Gu, Lijun
, p. 2443 - 2447 (2015/05/04)
A highly efficient and mild [bmIm]OH-catalyzed α-hydroxylation of phosphonates using O2 as the oxygen source is described. The employment of ionic liquid under mild reaction conditions makes this transformation green and practical. Especially, this reaction provided a novel and convenient methodology for the construction of quaternary α-hydroxy phosphonates.
Solvent-free synthesis of Tertiaryα-Hydroxyphosphates by the Triethylamine-catalyzed hydrophosphonylation of ketones
Wang, Chubei,Zhou, Jianwei,Lv, Xingbin,Wen, Junlei,He, Hongwu
, p. 1334 - 1339 (2013/10/08)
A new, environmentally benign, convenient, and easy method of synthesizing tertiary α-hydroxyphosphonates by the triethylamine-catalyzed hydrophosphonylation of unactivated ketones was developed. In the presence of triethylamine, aromatic or heteroaromati
Reactions of acyl phosphonates with organoaluminum reagents: A new method for the synthesis of secondary and tertiary α-hydroxy phosphonates
Seven, Ozlem,Polat-Cakir, Sidika,Hossain, Md. Shakhawoat,Emrullahoglu, Mustafa,Demir, Ayhan S.
, p. 3464 - 3469 (2011/06/19)
The reactions of organoaluminum reagents (trimethylaluminum, triethylaluminum, etc.) with aryl and alkyl acyl phosphonates, which lead to the formation of α-hydroxy phosphonates in moderate to good yields, are reported. This method provides easy access to
