401613-74-9

Upstream product

• 98-88-4 benzoyl chloride 
• 230309-05-4 (4S)-(4-tert-butyl-2-thioxo-1,3-diazolidin-3-yl)-pyridin-3-yl-methanone 
• 255828-69-4 (4S)-4-tert-butyl-1,3-thiazolidine-2-thione 
• 591-51-5 phenyllithium 

Downstream Products

• 230309-16-7 (S)-4-phenyl-1,4-dihydropyridin-3-carboxylic acid methyl ester 
• 230309-17-8 (S)-4-phenyl-1,4,5,6-tetrahydropyridin-3-carboxylic acid methyl ester 
• 230309-18-9 4-phenylpiperidine-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Regio- and stereoselective synthesis of 1,4-dihydropyridines by way of an intramolecular interaction of a thiocarbonyl or carbonyl with a pyridinium nucleus

Chiral 1,4-dihydropyridines were prepared by the regio- and stereoselective addition of ketene silyl acetals and organometallic reagents to pyridinium salts. In the addition reaction, an intramolecular interaction between the thiocarbonyl or carbonyl with

Synthesis of chiral 1,4-dihydropyridines by diastereoface-selective asymmetric addition to nicotinic amides

Diastereoface-selective asymmetric addition of organometallic reagents to pyridinium salts of 1 and 2 was performed to give chiral 1,4-dihydropyridines in good regio- and stereoselectivities. The absolute configuration of the newly-produced chiral center