40162-62-7Relevant academic research and scientific papers
One-Pot Conversion of Fluorenylmethyl Carbamates into tert-Butyl Carbamates
Li, Wen-Ren,Jiang, Jianjun,Joullie, Madelaine M.
, p. 1413 - 1414 (1993)
N-Fluorenylmethoxycarbonyl groups may be efficiently converted into N-tert-butoxycarbonyl groups by potassium fluoride/Et3N in the presence of Boc2O.
Phenysilane and Silicon Tetraacetate: Versatile Promotors for Amide Synthesis
Morisset, Eléonore,Chardon, Aurélien,Rouden, Jacques,Blanchet, Jér?me
supporting information, p. 388 - 392 (2020/01/24)
Phenylsilane was reevaluated as a useful coupling reagent for amide synthesis. At room temperature, a wide range of amides and peptides were obtained in good to excellent yields (up to 99 %). For the first time, Weinreb amides synthesis mediated by a hydrosilane were also documented. Comparative experiments with various acetoxysilanes suggested the involvement of a phenyl-triacyloxysilane. From this mechanistic study, silicon tetraacetate was shown as an efficient amine acylating agent.
tert-Butyloxycarbonyl and Benzyloxycarbonyl Amino Acid Fluorides. New, Stable Rapid-Acting Acylating Agents for Peptide Synthesis
Carpino, Louis A.,Mansour, El-Sayed M. E.,Sadat-Aalaee, Dean
, p. 2611 - 2614 (2007/10/02)
A new class of rapid-acting acylating agents, α-BOC and Z amino acid fluorides are obtained as stable, often crystalline, compounds by treatment of the protected amino acid cyanuric fluoride.
