40163-47-1Relevant academic research and scientific papers
Efficient Synthesis of 1-Ethyl-2,3,4,6,7,12-hexahydroindoloquinolizine: a Key Precursor to Eburnane Alkaloids
Danieli, Bruno,Lesma, Giordano,Palmisano, Giovanni
, p. 109 (1980)
The title compond has been conveniently synthesized from the imine (3) by cyclisation with acrylic acid followed by reduction.
EASY PREPARATION OF INDOLOQUINOLIZIDINE ENAMINES
Lounasmaa, Mauri,Karvinen, Esko
, p. 489 - 497 (2007/10/02)
A new and efficient synthesis of indoloquinolizidine enamines, including the highly valuable Wenkert's enamine (9a), is described.The behaviour of enamines (9a) and (9b) under reductive conditions was investigated.
NOVEL APPLICATIONS OF THE MODIFIED POLONOVSKI REACTION - IX A NEW ROUTE TO WENKERT'S ENAMINE
Lounasmaa, Mauri,Karvinen, Esko,Koskinen, Ari,Jokela, Reija
, p. 2135 - 2146 (2007/10/02)
A practical synthetic entry to Wenkert's enamine 1 employing the modified Polonovski reaction is described.Complete 13 C NMR spectral data of 1 is presented.Conformational analysis of the intermediate 1-hydroxy- and 1-ethyl-1-hydroxy-indoloquinolizidines
Synthesis of vinca alkaloids and related compounds, XV. A new synthetic route to (+)-vincaminic and (+)-apovincaminic esters
Szabo,Kalaus,Szantay
, p. 629 - 638 (2007/10/02)
Esters of types 7 and 8, possessing excellent vasodilating effects, have been prepared. A method has been found for the resolution of methyl ester 7c. A new method is described for the preparation of the lactam (+)-10 and its conversion to the oxime (+)-11, from which (+)-vincamine (1a) and the (+)-apovincaminic esters 2a,b were synthesized.
