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N-(chloro-tert-butyl)-benzamide is a chemical compound with the molecular formula C11H12ClNO. It is a derivative of benzamide, where a chloro-tert-butyl group is attached to the nitrogen atom. N-(chloro-tert-butyl)-benzamide is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly as a precursor in the production of certain active ingredients. It is characterized by its reactivity and stability, which can be leveraged in various chemical transformations. The compound is typically synthesized through a reaction involving benzoic acid and chloro-tert-butylamine, followed by amide formation. Due to its reactivity, it is often used in the preparation of intermediates for further chemical modifications, highlighting its importance in organic synthesis and the development of new molecules with specific therapeutic or pesticidal properties.

40186-36-5

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40186-36-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 40186-36-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,1,8 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40186-36:
(7*4)+(6*0)+(5*1)+(4*8)+(3*6)+(2*3)+(1*6)=95
95 % 10 = 5
So 40186-36-5 is a valid CAS Registry Number.

40186-36-5Relevant academic research and scientific papers

Ru(II)-Pheox catalyzed N-H insertion reaction of diazoacetamides: Synthesis of N-substituted α-aminoamides

Chanthamath, Soda,Thongjareun, Songkharm,Shibatomi, Kazutaka,Iwasa, Seiji

, p. 4862 - 4865 (2012/09/08)

An efficient protocol for the preparation of α-aminoamides was developed via the Ru(II)-dm-Pheox catalyzed N-H insertion reaction of various diazoacetamides with several amines, including aniline. This catalytic N-H insertion reaction was also applied to the synthesis of 2-(2-methylquinolin-4- ylamino)-N-phenylacetamide, a potential antileishmanial agent.

Highly stereoselective Ru(ii)-Pheox catalyzed asymmetric cyclopropanation of terminal olefins with succinimidyl diazoacetate

Chanthamath, Soda,Phomkeona, Kesiny,Shibatomi, Kazutaka,Iwasa, Seiji

supporting information; experimental part, p. 7750 - 7752 (2012/09/21)

The Ru(ii)-Pheox complex is an efficient catalyst for the intermolecular cyclopropanation of various terminal olefins with succinimidyl diazoacetate. This catalytic system can perform under mild conditions, and the desired cyclopropane products are obtain

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