40188-34-9

Usage

Uses

Used in Organic Synthesis:
2,4,6-trimethylbenzaldehyde oxime is used as a building block for the preparation of various organic compounds, contributing to the synthesis of a wide range of chemical products.
Used in Pharmaceutical Synthesis:
2,4,6-trimethylbenzaldehyde oxime is used as a reagent in the preparation of N-heterocyclic carbene complexes, which are important intermediates in the synthesis of pharmaceuticals. These complexes play a crucial role in the development of new drugs.
Used in Agrochemical Synthesis:
2,4,6-trimethylbenzaldehyde oxime is also utilized in the synthesis of agrochemicals, specifically as a reagent for N-heterocyclic carbene complexes, which are vital in creating effective agricultural chemicals.
Used in Materials Science:
2,4,6-trimethylbenzaldehyde oxime has applications in materials science, particularly in the development of new materials through its role as a reagent in the synthesis of N-heterocyclic carbene complexes.
Used in Metal Protection:
2,4,6-trimethylbenzaldehyde oxime has been studied for its potential use as a corrosion inhibitor in metal protection applications. It is recognized for its ability to form protective films on metal surfaces, enhancing their durability and resistance to corrosion.

Upstream product

• 707-74-4 (trichloromethyl)mesitylene 
• 75-52-5 nitromethane 
• 108-67-8 1,3,5-trimethyl-benzene 

Downstream Products

• 49623-42-9 mesitonitrile oxide 
• 75781-28-1 C₁₀H₁₂NO 
• 2904-63-4 2,4,6-trimethylbenzohydroximoyl chloride 
• 2904-57-6 mesitylenecarbonitrile oxide 
• 2571-52-0 cyanomesitylene 
• 487-68-3 mesytaldehyde 
• 81517-97-7 methyl N-(2,4,6-trimethylphenyl)carbamate 
• 70464-65-2 5-phenyl-3-(2,4,6-trimethyl-phenyl)-(3ar,6ac)-3a,6a-dihydro-pyrrolo[3,4-d]isoxazole-4,6-dione 
• 108295-19-8 cis-Dimethyl-3-(2,4,6-trimethylphenyl)-4,5-dihydro-4,5-isoxazoledicarboxylate 
• 782450-79-7 O-{(1S)-[3-(2,3,6-trimethyl-phenyl)-isoxazol-5-yl]-ethyl}-hydroxylamine 
• 89-51-0 Homophthalic acid 
• 480-63-7 mesitylenecarboxylic acid 
• 22234-62-4 1,3,5-trimethyl-2-(nitromethyl)benzene 
• 55609-49-9 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-cyclohepta[d]isoxazol-4-one 

Relevant academic research and scientific papers

Efficient transformation of electron-rich arenes into diethyl 3-arylisoxazole-4,5-dicarboxylates

Treatment of electron-rich arenes with Tf2O and DMF, followed by the reaction with NH2OH·HCl and then with Oxone in the presence of diethyl acetylenedicarboxylate generated diethyl 3-arylisoxazole-4,5-dicarboxylates in good to modera

Aluminium chloride promoted carbohydroximoylation reaction of aromatic compounds with primary nitroalkanes

The reaction of primary nitroalkanes with aromatic compounds in the presence of aluminium chloride afforded the corresponding carbohydroximoylated aromatic compounds.

Initial steps in the reductive condensation of trichloromethylarenes with hydroxylamine and hydrazines in pyridine

Data concerning the initial steps in the reductive condensation of trichloromethylarenes with hydroxylamine or hydrazines in pyridine have been obtained.High yields of the products of the reductive condensation obtained even at equimolar ratios of trichloromethylarene with hydroxylamine or hydrazine as well as the formation of unusual products, i.e., 4-pyridylhydrazones of substituted benzaldehydes, have been interpreted as the results of the participation of pyridine in the reaction as a reductive agent. - Key words: trichloromethylarenes, reductive condensation with hydroxylamine or hydrazines, role of pyridine; 4-pyridylhydrazones of substituted benhaldehydes.

Reductive condensation of trichloromethylarenes with hydroxylamine and hydrazines in pyridine

The interaction of trichloromethylarenes with hydroxylamine in pyridine involves the reductive oximation of aryltrichloromethanes. Further transformations of the oximes in the reaction course can result in the formation of nitriles or 3,5-diaryl-1,2,4-oxadiazoles as final products. The conversion depth depends on reaction conditions and structures of trichloromethyl-arenes. When hydrazines used instead of hydroxylamine, respectivebenzaldehyde hydrazones or azines are obtained.