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N-(3-methoxy-5-trifluoromethylphenyl)acetamide is a chemical compound with the molecular formula C10H10F3NO3. It is an amide derivative, characterized by the presence of an amide functional group (-CONH2) attached to a phenyl ring. The phenyl ring in N-(3-methoxy-5-trifluoromethylphenyl)acetamide is substituted with a methoxy group (-OCH3) at the 3rd position and a trifluoromethyl group (-CF3) at the 5th position. N-(3-methoxy-5-trifluoromethylphenyl)acetamide is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as in materials science. Its specific properties, such as solubility, stability, and reactivity, can be influenced by the electron-withdrawing nature of the trifluoromethyl group and the electron-donating nature of the methoxy group, making it a subject of interest in organic chemistry and medicinal chemistry research.

402-01-7

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402-01-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 402-01-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 402-01:
(5*4)+(4*0)+(3*2)+(2*0)+(1*1)=27
27 % 10 = 7
So 402-01-7 is a valid CAS Registry Number.

402-01-7Relevant academic research and scientific papers

Rhodium(III)-Catalyzed Tandem [2+2+2] Annulation–Lactamization of Anilides with Two Alkynoates via Cleavage of Two Adjacent C?H or C?H/C?O bonds

Fukui, Miho,Shibata, Yu,Hoshino, Yuki,Sugiyama, Haruki,Teraoka, Kota,Uekusa, Hidehiro,Noguchi, Keiichi,Tanaka, Ken

, p. 2260 - 2264 (2016)

An electron-deficient CpE rhodium(III) complex bearing a cyclopentadienyl ligand with two ethyl ester substituents catalyzes the tandem [2+2+2] annulation–lactamization of acetanilides with two alkynoates via cleavage of adjacent two C?H bonds to give densely substituted benzo[cd]indolones. The reactions of meta-methoxy-substituted acetanilides with two alkynoates also provided benzo[cd]indolones via cleavage of adjacent C?H/C?O bonds. Furthermore, 3,5-dimethoxyacetanilides reacted with two alkynoates to give dearomatized spiro compounds.

PYRIMIDINYL ARYL UREA DERIVATIVES BEING FGF INHIBITORS

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Page/Page column 88, (2008/06/13)

The invention relates to heteroaryl aryl ureas of the formula (IA), wherein the radicals and symbols have the meanings as defined herein, the use of such compounds in the treatment of protein kinase dependent diseases; to pharmaceutical preparations comprising said heteroaryl aryl ureas, to processes for the manufacture of such novel compounds and to methods of treatment comprising the use of such heteroaryl aryl ureas.

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