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3-cyanobenzenesulfonyl fluoride, also known as 3-cyanophenylsulfonyl fluoride, is a chemical compound with the molecular formula C7H4FNO2S. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents. 3-cyanobenzenesulfonyl fluoride is an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. It is used as a protecting group in organic synthesis, particularly in the protection of amines and alcohols, due to its stability and ease of removal under mild conditions. The compound is also known for its reactivity as a sulfonylating agent, which can be used to introduce sulfonyl groups into various organic molecules. It is important to handle 3-cyanobenzenesulfonyl fluoride with care due to its potential toxicity and reactivity.

402-27-7

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402-27-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 402-27-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 402-27:
(5*4)+(4*0)+(3*2)+(2*2)+(1*7)=37
37 % 10 = 7
So 402-27-7 is a valid CAS Registry Number.

402-27-7Upstream product

402-27-7Downstream Products

402-27-7Relevant articles and documents

Fluorosulfonylation of arenediazonium tetrafluoroborates with Na2S2O5 and N-fluorobenzenesulfonimide

Huang, Yangen,Liu, Shuai,Qing, Feng-Ling,Xu, Xiu-Hua

, (2020)

A transition-metal-free Sandmeyer-type fluorosulfonylation reaction has been achieved by the three-component reaction of arenediazonium tetrafluoroborates, Na2S2O5, and N-fluorobenzenesulfonimide (NFSI). The reaction proceeds through a radical tandem process, affording various arenesulfonyl fluorides in moderate to high yields. This protocol not only provides a complement to the previous fluorosulfonylation reactions, but also extends the applications of Sandmeyer reaction.

NOVEL COMPOUNDS

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Page/Page column 24; 35, (2008/06/13)

The present invention relates to novel indole derivatives such as compounds of the formula (I): which possess antagonist potency at the 5-HT6 receptor and the use of such compounds or pharmaceutically acceptable salts or solvates thereof in the treatment of Alzheimer's disease and other CNS disorders.

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