402-96-0

Basic information

• Product Name: 2-amino-1-(3-fluorophenyl)ethanol
• Synonyms: BENZENEMETHANOL, α-(AMINOMETHYL)-3-FLUORO-;2-amino-1-(3-fluorophenyl)ethanol;AKOS BBV-002803;2-Amino-1-(3-fluorophenyl)ethan-1-ol
• CAS NO: 402-96-0
• Molecular Formula: C₈H₁₀FNO
• Molecular Weight: 155.171
• Mol File: 402-96-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-1-(3-fluorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-1-(3-fluorophenyl)ethanol(402-96-0)
• EPA Substance Registry System: 2-amino-1-(3-fluorophenyl)ethanol(402-96-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 402-96-0(Hazardous Substances Data)

Usage

General Description

2-amino-1-(3-fluorophenyl)ethanol is a chemical compound with the molecular formula C8H2N1O1F3. It is a clear and colorless liquid that is frequently used in organic synthesis and chemical research. 2-amino-1-(3-fluorophenyl)ethanol is also known by the name o-(3-Fluorophenyl)ethanolamine and is often used as an intermediate in the production of pharmaceuticals and agrochemicals. It is important to handle this compound with care, as it is known to be hazardous if not properly managed.

Upstream product

• 100948-28-5 2-(3-fluorophenyl)-2-((trimethylsilyl)oxy)acetonitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant articles and documents

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

A series of 1-aryl-2-(((6-aryl)pyrimidin-4-yl)amino)ethanols have been found to be competitive inhibitors of fatty acid amide hydrolase (FAAH). One member of this class, JNJ-40413269, was found to have excellent pharmacokinetic properties, demonstrated robust central target engagement, and was efficacious in a rat model of neuropathic pain.

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase

A novel class of 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase is described. This report discusses the SAR of 4-(2-hydroxy-2-phenylethylamino)-substituted pyridones with improved IGF-1R potency.