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2-amino-1-(3-fluorophenyl)ethanol, also known as o-(3-Fluorophenyl)ethanolamine, is a chemical compound with the molecular formula C8H2N1O1F3. It is a clear and colorless liquid that is frequently used in organic synthesis and chemical research. 2-amino-1-(3-fluorophenyl)ethanol is also utilized as an intermediate in the production of pharmaceuticals and agrochemicals, making it a valuable component in the development of various chemical products.

402-96-0

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402-96-0 Usage

Uses

Used in Pharmaceutical Industry:
2-amino-1-(3-fluorophenyl)ethanol is used as an intermediate for the synthesis of various pharmaceuticals. Its unique structure and functional groups allow it to be incorporated into the development of new drugs, potentially leading to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-amino-1-(3-fluorophenyl)ethanol is used as a precursor in the production of agrochemicals. Its properties make it suitable for the synthesis of compounds that can be used in the development of pesticides, herbicides, and other agricultural chemicals to improve crop yields and protect plants from pests.
Used in Organic Synthesis:
2-amino-1-(3-fluorophenyl)ethanol is used as a reagent in organic synthesis for the preparation of various organic compounds. Its versatility in chemical reactions allows it to be a key component in the synthesis of a wide range of organic molecules, contributing to the advancement of chemical research and development.
It is important to handle 2-amino-1-(3-fluorophenyl)ethanol with care, as it is known to be hazardous if not properly managed. Proper safety measures should be taken during its use to ensure the safety of individuals and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 402-96-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 402-96:
(5*4)+(4*0)+(3*2)+(2*9)+(1*6)=50
50 % 10 = 0
So 402-96-0 is a valid CAS Registry Number.

402-96-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-1-(3-fluorophenyl)ethanol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:402-96-0 SDS

402-96-0Downstream Products

402-96-0Relevant academic research and scientific papers

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Keith, John M.,Hawryluk, Natalie,Apodaca, Richard L.,Chambers, Allison,Pierce, Joan M.,Seierstad, Mark,Palmer, James A.,Webb, Michael,Karbarz, Mark J.,Scott, Brian P.,Wilson, Sandy J.,Luo, Lin,Wennerholm, Michelle L.,Chang, Leon,Rizzolio, Michele,Chaplan, Sandra R.,Breitenbucher, J. Guy

, p. 1280 - 1284 (2014/03/21)

A series of 1-aryl-2-(((6-aryl)pyrimidin-4-yl)amino)ethanols have been found to be competitive inhibitors of fatty acid amide hydrolase (FAAH). One member of this class, JNJ-40413269, was found to have excellent pharmacokinetic properties, demonstrated robust central target engagement, and was efficacious in a rat model of neuropathic pain.

PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS

-

Page/Page column 42, (2010/11/30)

A compound of formula (I) or a salt or solvate thereof: Formula (1) compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such mono-anilino pyrimidine derivative

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase

Wittman, Mark D.,Balasubramanian, Balu,Stoffan, Karen,Velaparthi, Upender,Liu, Pieying,Krishnanathan, Subramaniam,Carboni, Joan,Li, Aixin,Greer, Ann,Attar, Ricardo,Gottardis, Marco,Chang, Chiehying,Jacobson, Bruce,Sun, Yax,Hansel, Steven,Zoeckler, Mary,Vyas, Dolatrai M.

, p. 974 - 977 (2007/10/03)

A novel class of 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase is described. This report discusses the SAR of 4-(2-hydroxy-2-phenylethylamino)-substituted pyridones with improved IGF-1R potency.

Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses

-

, (2008/06/13)

Compounds of formula (I): STR1 (wherein: R0 is hydrogen, methyl or hydroxymethyl; R1 is substituted alkyl; R2 and R3 are each hydrogen, halogen, hydroxy, alkoxy, carboxy, alkoxycarbonyl, alkyl, nitro, haloalkyl, or substituted alkyl; X is oxygen or sulfur; and Ar optionally substituted phenyl or naphthyl); and pharmaceutically acceptable salts thereof have a variety of valuable pharmaceutical activities, including anti-diabetic and anti-obesity activities; in addition, they are capable of treating or preventing hyperlipemia and hyperglycemia and, by inhibiting the action of aldose reductase, they can also be effective in the treatment and prevention of complications of diabetes.

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