40203-48-3Relevant academic research and scientific papers
Synthesis of highly electron-poor alkenes from in situ generated stabilized phosphorus ylides and ninhydrin via intermolecular Wittig reaction
Ramazani, Ali,Bodaghi, Ali
, p. 1615 - 1620 (2004)
Protonation of the highly reactive 1:1 intermediates, produced in the reaction between triphenylphosphine and dialkyl acetylenedicarboxylates, by alcohols leads to vinyltriphenylphosphonium salts, which undergo Michael addition reaction with conjugate base to produce the corresponding stabilized phosphorus ylides. Intermolecular Wittig reaction of the stabilized phosphorus ylides with ninhydrin leads to the corresponding, highly electron-poor alkenes.
Novel stereoselective synthesis of densely functionalized 2H-indeno[2,1-b]furans
Noshiranzadeh, Nader,Ramazani, Ali,Slepokura, Katarzyna,Lis, Tadeusz
, p. 1560 - 1568 (2008)
An easy access to densely functionalized 2H-indeno[2,1-b]furans is presented starting from triphenylphosphine, dialkyl acetylenedicarboxylates, alcohols (propargyl alcohol, 2,2,2-trichloroethanol, and methanol), and ninhydrin. The stereochemistry of dimethyl 8-oxo-8a-(2,2,2-trichloroethoxy)-8, 8a-dihydro-2H-indeno[2,1-b]furan-2,3-dicarboxylate was established by single-crystal X-ray structure determination. The reaction is completely stereoselective. Copyright Taylor & Francis Group, LLC.
