40205-21-8Relevant academic research and scientific papers
Synthesis, inhibition of mycobacterium tuberculosis enoyl-acyl carrier protein reductase and antimycobacterial activity of novel pentacyanoferrate(II)-isonicotinoylhydrazones
Gazzi, Thais P.,Rotta, Mariane,Villela, Anne D.,Rodrigues, Valn's,Martinelli, Leonardo K.B.,Sales, Francisco Adilson M.,Silva De Sousa, Eduardo Henrique,Campos, Maria Martha,Basso, Luiz Augusto,Santos, Diógenes S.,Machado, Pablo
, p. 2028 - 2037 (2017)
Tuberculosis remains among the top causes of death triggered by a single pathogen. Herein, a greener synthetic approach for isonicotinoylhydrazones is described using ultrasound energy. These compounds were used as starting materials for synthesizing pent
Design and synthesis of novel N-substituted-3-chloro-2- azetidinone derivatives as potential anticonvulsant agents
Hasan, Hozaifa,Akhter, Maymoona,Akhter, Wasim,Ali, Israr,Zaheen, Mohd.,Ahsan, Iftikhar,Mahmood, Danish
supporting information; experimental part, p. 1357 - 1363 (2012/06/04)
A new series of N-[3-chloro-2-(substitutedphenyl)-oxo-azetidin-1-yl] isonicotinamide (2a-l) were synthesized through condensation reaction of isoniazide with substituted aldehyde. The newly synthesized compounds ere characterized by spectral data (IR, su
Lipophilic analogs of isoniazid with antiproliferative in vitro activity-VIII
Vigorita, Maria Gabriella,Maccari, Rosanna,Ottana, Rosaria,Monforte, Francesca
, p. 306 - 321 (2007/10/03)
Five series of differently-featured Isoniazid (INH) analogs were synthesized and investigated with the aim of extending the specific bioactivity of the parent-drug to AIDS-associated pathologies other than tuberculosis. All compounds were found to be more
COMPLEXES OF NICOTINOYL- AND ISONICOTINOYL HYDRAZONE SCHIFF BASES WITH DIVALENT METAL IONS
Agarwala, Badri Vishal,Reddy, Pindi Satya Narayana
, p. 269 - 275 (2007/10/02)
New divalent metal complexes of hydrazone Schiff bases are synthesized by first reacting nicotinoyl- or isonicotinoyl hydrazine with anisaldehyde.The spectral data of the chelating ligands (ANH, AINH) show that AINH functions as a bidentate (NO) donor whereas ANH functions as a tridentate (NON) donor.A negative shift in the stretching frequency of pyridine ring nitrogen atom indicates the involvement of the latter in coordination.Octahedral structures are assigned on the basis of elemental analysis, infrared and diffuse reflectance spectra, magnetic and thermal studies.
