4021-75-4

Basic information

• Product Name: 2,3-dibromobutan-1-ol
• Synonyms: 2,3-Dibromobutanol; Butanol, 2,3-dibromo-
• CAS NO: 4021-75-4
• Molecular Formula: C₄H₈Br₂O
• Molecular Weight: 231.9137
• Mol File: 4021-75-4.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 249.6°C at 760 mmHg
• Flash Point: 104.8°C
• Density: 1.945g/cm³
• Vapor Pressure: 0.00363mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 2,3-dibromobutan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromobutan-1-ol(4021-75-4)
• EPA Substance Registry System: 2,3-dibromobutan-1-ol(4021-75-4)

Safety Data

• Hazardous Substances Data: 4021-75-4(Hazardous Substances Data)

Usage

General Description

2,3-dibromobutan-1-ol is a chemical compound with the molecular formula C4H8Br2O. It is a colorless, odorless liquid that is used in various chemical reactions and processes. The compound is derived from butan-1-ol, with bromine atoms attached to the second and third carbon atoms. It is primarily used as an intermediate in the synthesis of other organic compounds and is also used as a reagent in organic chemistry reactions. 2,3-dibromobutan-1-ol is a versatile compound with a variety of potential uses in the field of organic chemistry. It is important to handle and store this chemical compound with caution due to its potential hazards.

Upstream product

• 4088-60-2 cis-2-buten-1-ol 
• 504-61-0 (E)-but-2-enol 
• 6117-91-5 (E/Z)-2-buten-1-ol 
• 123-73-9 trans-Crotonaldehyde 
• 4021-75-4 (2R*,3R*)-2,3-dibromobutan-1-ol 

Downstream Products

• 600-30-6 erythro-2,3-dibromobutanoic acid 
• 52467-65-9 (Z)-2-bromobut-2-en-1-ol 
• 6117-91-5 (E/Z)-2-buten-1-ol 
• 4021-75-4 (–)-(2S,3S)-2,3-dibromobutan-1-ol 
• 4021-75-4 threo-2,3-Dibrombutan-1-ol 
• 632-05-3 1,2,3-tribromobutane 

Relevant articles and documents

COMPOUNDS USEFUL IN INHIBITING KETOHEXOKINASE AND METHODS OF MAKING AND USING THE SAME

The present invention relates to compounds that can act as inhibitors of ketohexokinase (KHK) and that can be useful in the treatment of diseases and/or disorders associated with KHK. In some embodiments, the present invention relates to compounds and com

Molecular Recognition and Cocrystallization of Methylated and Halogenated Fragments of Danicalipin A by Enantiopure Alleno-Acetylenic Cage Receptors

Enantiopure (P)4- and (M)4-configured alleno-acetylenic cage (AAC) receptors offer a highly defined interior for the complexation and structure elucidation of small molecule fragments of the stereochemically complex chlorosulfolipid danicalipin A. Solution (NMR), solid state (X-ray), and theoretical investigations of the formed host-guest complexes provide insight into the conformational preferences of 14 achiral and chiral derivatives of the danicalipin A chlorohydrin core in a confined, mostly hydrophobic environment, extending previously reported studies in polar solvents. The conserved binding mode of the guests permits deciphering the effect of functional group replacements on Gibbs binding energies ΔG. A strong contribution of conformational energies toward the binding affinities is revealed, which explains why the denser packing of larger apolar domains of the guests does not necessarily lead to higher association. Enantioselective binding of chiral guests, with energetic differences ΔΔG293 K up to 0.7 kcal mol-1 between diastereoisomeric complexes, is explained by hydrogen- and halogen-bonding, as well as dispersion interactions. Calorimetric studies (ITC) show that the stronger binding of one enantiomer is accompanied by an increased gain in enthalpy ΔH but at the cost of a larger entropic penalty TΔS stemming from tighter binding.

SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANES AS KETOHEXOKINASE INHIBITORS

Provided herein are substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.