40221-64-5Relevant academic research and scientific papers
Cu(II) complex of an abiotic receptor as highly selective fluorescent sensor for acetate
Goswami, Shyamaprosad,Chakrabarty, Rinku
, p. 5994 - 5997 (2009)
A copper complex having quinoline moiety as fluorophore has been synthesized. The anion recognition behavior of the receptor and its copper complex has been studied in acetonitrile and in acetonitrile: H2O (95:5 v/v). The copper complex shows high selectivity toward acetate over other anions studied such as F-, Cl-, Br-, I-, OAc-, dl-malate, l-mandelate, benzoate, isophthalate, H2 PO4-, NO3- and HSO4-.
Bisphosphonate sequestering agents. Synthesis and preliminary evaluation for in vitro and in vivo uranium(VI) chelation
Sawicki, Marcin,Lecercle, Delphine,Grillon, Gerard,Le Gall, Beatrice,Serandour, Anne-Laure,Poncy, Jean-Luc,Bailly, Theodorine,Burgada, Ramon,Lecouvey, Marc,Challeix, Vincent,Leydier, Antoine,Pellet-Rostaing, Stephane,Ansoborlo, Eric,Taran, Frederic
experimental part, p. 2768 - 2777 (2009/04/06)
A library of bisphosphonate-based ligands was prepared using solution-phase parallel synthesis and tested for its uranium-binding properties. With the help of a screening method, based on a chromophoric complex displacement procedure, 23 dipodal and tripodal chelates bearing bisphosphonate chelating functions were found to display very high affinity for the uranyl ion and were selected for evaluation of their in vivo uranyl-removal efficacy. Among them, 11 ligands induced a huge modification of the uranyl biodistribution by deviating the metal from kidney and bones to liver. Among the other ligands, the most potent was the dipodal bisphosphonate 3C which reduced the retention of uranyl and increased its excretion by around 10% of the injected metal.
