40235-35-6Relevant academic research and scientific papers
Palladium-catalyzed aerobic oxidative C-H olefination with removable 1,2,3-triazole directing group
Ye, Xiaohan,Shi, Xiaodong
supporting information, p. 4448 - 4451 (2015/01/09)
Ortho-olefination of arenes was achieved with removable 1,2,3-triazole auxiliary through Pd-catalyzed C-H activation. Excellent yields were received even when molecular O2 (1 atm) was used as the terminal oxidant. Other heterocyclic directing groups, such as pyridine and quinoline, gave poor reactivity under this aerobic oxidative condition, which highlighted the unique reactivity of triazole in promoting directed C-H activation.
α-Haloacrylates as acceptors in the [3 + 2] cycloaddition reaction with NaN3: An expedient approach to N-unsubstituted 1,2,3-triazole-4-carboxylates
Augustine, John Kallikat,Boodappa, Chandrakantha,Venkatachaliah, Srinivasa
, p. 2280 - 2288 (2014/04/03)
An expedient synthesis of N-unsubstituted 1,2,3-triazole-4-carboxylates has been demonstrated through [3 + 2] cycloaddition of sodium azide with α-haloacrylates. The process is highly reliable and exhibits an unusually wide scope with respect to α-fluoro-
