40244-90-4

Usage

Uses

1. Used in Chemical Synthesis:
Chlorodiisopropylphosphine is used as a reagent for the synthesis of p-styryldiisopropylphosphine by reacting with 4-chlorostyrene via a Grignard reaction. This reaction is crucial in the production of various organic compounds and pharmaceuticals.
2. Used as a Phosphination Reagent:
In the field of organometallic chemistry, chlorodiisopropylphosphine is used as a phosphination reagent in combination with [Cp2Zr(1-butene)(DMAP)] (Cp=cyclopentadienyl; DMAP= 4-(dimethylamino)pyridine) for the zirconophosphination of alkynes. This process leads to the formation of zirconoalkenylphosphines, which are important intermediates in the synthesis of complex organic molecules.
3. Used in the Synthesis of Luminescent Complexes:
Chlorodiisopropylphosphine is also utilized in the synthesis of a luminescent mixed-donor platinum POCN pincer complex via a cyclometalation process. These complexes have potential applications in the field of optoelectronics and as sensors for various analytes.
4. Used in the Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, chlorodiisopropylphosphine can be used in the pharmaceutical industry for the synthesis of various drugs and drug candidates, particularly those involving organophosphorus chemistry.
5. Used in the Agrochemical Industry:
Similar to the pharmaceutical industry, chlorodiisopropylphosphine can be employed in the agrochemical industry for the synthesis of pesticides, herbicides, and other chemical products used in agriculture.

InChI:InChI=1/C6H14ClP/c1-5(2)8(7)6(3)4/h5-6H,1-4H3

Upstream product

• 686-69-1 diethylchlorophosphine 
• 131551-78-5 C₁₅H₃₂OP₂ 
• 62969-12-4 tetraisopropyldiphosphine monosulfide 
• 4885-02-3 Dichloromethyl methyl ether 
• 95987-39-6 (diethoxymethyl)diisopropylphosphine oxide 
• 41839-38-7 1,1-dibutoxy-2,2-diisopropyl-diphosphane 
• 644-97-3 Dichlorophenylphosphine 
• 1068-55-9 isopropylmagnesium chloride 
• 59612-04-3 diisopropylphosphinous iodide 
• 75-29-6 isopropyl chloride 
• 25235-15-8 dichloroisopropylphosphine 

Downstream Products

• 116006-33-8 ((E)-2-Cyclohex-1-enyl-vinyl)-diisopropyl-phosphane 
• 84761-42-2 diisopropyl(ortho-anisyl)phosphine 
• 84998-58-3 Diisopropylphosphinigsaeure-o-bromphenylester 
• 139424-60-5 diisopropylphosphinous acid trimethylhydrazide 
• 70589-63-8 C₁₂H₁₉BrNP 
• 66480-33-9 1-cyclohexen-1-yl diisopropylphosphinite 
• 66480-34-0 2-Diisopropylphosphanyl-cyclohexanone 
• 66480-35-1 C₁₈H₃₆OP₂ 
• 66480-39-5 C₁₅H₂₃OP 
• 66480-42-0 C₁₆H₂₅OP 
• 140173-18-8 Cyclohexyl-(2-diisopropylphosphanyl-cyclohex-1-enyl)-amine 
• 140173-19-9 Cyclohexyl-(2-diisopropylphosphanyl-cyclopent-1-enyl)-amine 
• 264259-02-1 4,6-di-tert-butyl-2-(diisopropylphosphanyl)phenol 
• 434336-17-1 2,2'-bis(diisopropylphosphino)diphenyl ether 

Relevant academic research and scientific papers

Reactions of Silicon-Silicon Bonds, VI. Reductive Trichlorosilylation Reactions Leading to Alkyl- and Dialkylaminobis(trichlorosilyl)phosphanes

Reactions of hexachlorodisilane and of trichlorosilane/triethylamine with alkyl- and dialkylaminodichlorophosphanes RPCl2 1a-f furnish bis(trichlorosilyl)phosphanes RP(SiCl3)2 3a-f.However, when less bulky substituents are attached to the phosphorus atom, so that there is little steric crowding, the double reductive silylations leading from 1 to 3 are accompanied by side reactions and decomposition of 3.Therefore, only 3b, 3c, 3d and 3f were isolated in a pure state.These compounds are more readily prepared by the trichlorosilane/triethylamine method. 1H-, 31P- and 29Si-NMR spectra confirm their constitution.The structure of solid 3f, the first aminobis(trichlorosilyl)phosphane, was determined by X-ray crystallography. 3f contains a phosphorus atom in a pyramidal environment surrounded by two silicon atoms and a planar nitrogen atom of the diisopropylamino group. - Keywords: Trichlorosilylation; Dichlorophosphanes; Silylphosphanes; Amino(silyl)phosphanes; Silicon; Reductions

Haloalkylation process

A process for the haloalkylation of certain tin, phosphorus and germanium halides is disclosed. The process is carried out typically in a halocarbon solvent at temperatures of less than 0° C. using as the haloalkylating reagent an admixture of a haloalkyl halide and tris(lower alkylamino)phosphine.

ZUR KENNTNIS DER ORGANOPHOSPHORVERBINDUNGEN, XXI. Darstellung von Organobromphosphanen aus RPCl2 und R2PCl durch Halogenaustausch.

Several methods for the preparation of organobromophosphanes from RPCl2 and R2PCl by halogen exchange are described.In case of aryl compounds optimal results are obtained by equilibration of the chlorophosphanes with PBr3 followed by distillation or cryst