402572-22-9

Upstream product

• 67-56-1 methanol 
• 138851-30-6 5-(2,2-dicyanoethenyl)salicylic acid 

Downstream Products

• 402572-33-2 2-amino-4-(4-hydroxy-3-methoxycarbonylphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyran-3-carbonitrile 
• 402572-24-1 6-amino-1,4-dihydro-4-(4-hydroxy-3-methoxycarbonylphenyl)-3-methylpyrano[2,3-c]-pyrazole-5-carbonitrile 

Relevant academic research and scientific papers

Simple synthesis of condensed pyran containing compounds and their antimicrobial properties

Reaction of various fused pyran compounds with formic acid was studied. Thus, refluxing 6-aminopyrano[2,3-c]pyrazole-5-carbonitriles 3 with formic acid afforded the corresponding 3-aryl-3-(5-hydroxy-3-methyl-1H-pyrazole-4-yl)propanoic acids 4. Whereas, reaction of formic acid with 2-amino-4H-1-benzopyran-3-carbonitriles 6 gave the corresponding quinoline-2,5(1H,6H)-diones 7. The study was also extended towards many spiro compounds possessing pyran residue. The antimicrobial properties of the prepared compounds was screened.