402616-45-9

Upstream product

• 501-53-1 benzyl chloroformate 
• 162359-55-9 fingolimod 
• 100-52-7 benzaldehyde 
• 402616-41-5 2-(benzyloxycarbonyl)amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol 
• 402616-43-7 2-phenyl-4-(benzyloxycarbonylamino)-4-(4-(octyl)phenyl)-1,3-dioxane 

Relevant academic research and scientific papers

Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720

The novel immunosuppressive agent FTY720 (1) is phosphorylated in vivo in a variety of species yielding an active metabolite that is an agonist of four of the five known G-protein-coupled sphingosine-1-phosphate (S1P) receptors. A synthesis amenable to pr

Phosphate derivatives as immunoregulatory agents

Immunoregulatory compounds are disclosed of the formula: and as well as the pharmaceutically acceptable salts and hydrates thereof, are disclosed. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.