40263-66-9Relevant academic research and scientific papers
Nitrile-Stabilized Carboanions. Nucleophilic Substitution Reactions on Bromopyridines
Newkome, George R.,Joo, Young J.,Evans, David W.,Pappalardo, Sebastiano,Fronczek, Frank R.
, p. 786 - 790 (1988)
A series of bis(2-heteroaryl)acetonitriles were synthesized, characterized, and transformed into the corresponding bis(2-heteroaryl)methanes, which can be readily oxidized with SeO2 in glacial acetic acid to the respective ketones.These disubstituted acetonitriles are ideal precursors to heterocalixarenes.The configuration in the solid state of meso-cyano compound 16 was ascertained by an X-ray crystal structure.
