40279-97-8

Basic information

• Product Name: 2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-3-PHENYLPROPANOIC ACID
• Synonyms: 2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-3-PHENYLPROPANOIC ACID;2-(4-Chloro-benzenesulfonylamino)-3-phenyl-propionic acid;2-[(4-chlorophenyl)sulfonylamino]-3-phenyl-propionic acid;N-[(4-chlorophenyl)sulfonyl]phenylalanine;(2S)-2-[(4-chlorophenyl)sulfonylamino]-3-phenylpropanoic acid;(2S)-2-[(4-chlorophenyl)sulfonylamino]-3-phenyl-propanoic acid;(2S)-2-[(4-chlorophenyl)sulfonylamino]-3-phenyl-propionic acid;(S)-2-(4-chlorophenylsulfonamido)-3-phenylpropanoic acid
• CAS NO: 40279-97-8
• Molecular Formula: C₁₅H₁₄ClNO₄S
• Molecular Weight: 339.79
• Mol File: 40279-97-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 147-149°C
• Boiling Point: 531.3°C at 760 mmHg
• Flash Point: 275.1°C
• Appearance: /
• Vapor Pressure: 4.05E-12mmHg at 25°C
• CAS DataBase Reference: 2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-3-PHENYLPROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-3-PHENYLPROPANOIC ACID(40279-97-8)
• EPA Substance Registry System: 2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-3-PHENYLPROPANOIC ACID(40279-97-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 40279-97-8(Hazardous Substances Data)

Usage

General Description

2-([(4-Chlorophenyl)sulfonyl]amino)-3-phenylpropanoic acid is a chemical compound with the molecular formula C15H15ClNO4S. It is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain natural substances that cause inflammation in the body. 2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-3-PHENYLPROPANOIC ACID is often used to relieve pain and reduce inflammation in conditions such as arthritis, menstrual cramps, and other forms of acute and chronic pain. It is a derivative of propionic acid and is commonly found in medications such as Celecoxib and Etoricoxib. The potential side effects of this compound include stomach upset, heartburn, and headache. It should be used with caution and under the supervision of a healthcare professional.

InChI:InChI=1/C15H14ClNO4S/c16-12-6-8-13(9-7-12)22(20,21)17-14(15(18)19)10-11-4-2-1-3-5-11/h1-9,14,17H,10H2,(H,18,19)/p-1/t14-/m1/s1

Upstream product

• 673-06-3 D-(R)-phenylalanine 
• 98-60-2 4-chlorobenzenesulfonyl chloride 

Downstream Products

• 944705-39-9 N-[2-(N'-acetyl-hydrazino)-1-benzyl-2-oxo-ethyl]-4-chloro-benzenesulfonamide 
• 169186-36-1 (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(ethoxycarbonylmethyl)phenyl)-3-phenylpropanamide 
• 169186-38-3 (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(2-methoxycarbonylethyl)phenyl)-3-phenylpropanamide 

Relevant articles and documents

CHEMICAL COMPOUNDS

The invention relates to chemical compounds of formula (I) and (II) or pharmaceutically acceptable salts thereof, which possess Edg-1 antagonistic activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.