402822-63-3Relevant academic research and scientific papers
Palladium-catalyzed R2(O)P directed C(sp2)-H acetoxylation
Zhang, Heng,Hu, Rong-Bin,Zhang, Xiao-Yu,Li, Shi-Xia,Yang, Shang-Dong
supporting information, p. 4686 - 4689 (2014/05/06)
A novel and efficient Pd-catalyzed C-H acetoxylation is described. The approach uses R2(O)P as a directing group to synthesize various substituted 2′-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields. This journal is the Partner Organisations 2014.
Palladium-catalyzed direct synthesis of phosphole derivatives from triarylphosphines through cleavage of carbon-hydrogen and carbon-phosphorus bonds
Baba, Katsuaki,Tobisu, Mamoru,Chatani, Naoto
supporting information, p. 11892 - 11895 (2013/11/19)
(Phosp)hole in one: A palladium-catalyzed synthesis for directly assembling phosphole skeletons from triarylphosphines through C-H and C-P bond cleavage was developed. This approach overcomes several of the limitations of the so far reported methods. Phospholes bearing a range of functionalities (including Br, F, CO2Me, Ac, and CN) and an array of fused rings (naphthalenes, anthracenes, furans, and pyrroles) can be easily synthesized. Copyright
Palladium-catalysed synthesis of biaryl phosphines
Baillie, Colin,Xiao, Jianliang
, p. 4159 - 4168 (2007/10/03)
Monodentate, biphenyl-type phosphines have emerged as a powerful class of ligands in homogeneous catalysis. Synthetic methods for these ligands are limited, however. We report that the palladium-catalysed Suzuki coupling of OPR2(o-C6H4X) (R=Ph, t-Bu; X=Br, I) with arylboronic acids affords a variety of biaryl phosphine oxides including those that contain heterocycles. The corresponding phosphines are readily obtained by treatment with HSiCl3. The methodology provides an easy entry to monodentate biaryl and heterobiaryl Poverlapping logical AND signX (X=N, O, S) phosphines with diverse steric and electronic properties.
Synthesis of biphenyl-based phosphines by Suzuki coupling
Baillie, Colin,Chen, Weiping,Xiao, Jianliang
, p. 9085 - 9088 (2007/10/03)
A series of phosphine oxides has been synthesised by the palladium-catalysed Suzuki coupling of arylboronic acids with OPPh2(o-C6H4Br). On reduction with trichlorosilane, functionalised, biphenyl-based phosphine ligands were obtained in good yields. Our preliminary results indicate these ligands to be effective for palladium-catalysed C-C coupling reactions including the formation of their own oxides.
