402822-72-4

Basic information

• Product Name: 2-(Diphenylphosphino)-2'-methylbiphenyl
• Synonyms: 2-(Diphenylphosphino)-2'-methylbiphenyl;(2'-Methyl-[1,1'-biphenyl]-2-yl)diphenylphosphine;2-(DiphenylphosphiNA)-2'-Methylbiphenyl;2-(Diphenylphosphino)-2'-Methy;(2'-Methylbiphenyl-2-yl)diphenylphosphine;(2'-Methyl-[1,1'-biphenyl]-2-yl)
• CAS NO: 402822-72-4
• Molecular Formula: C₂₅H₂₁P
• Molecular Weight: 352.408001
• EINECS: 1312995-182-4
• Mol File: 402822-72-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 472.6±24.0 °C(Predicted)
• Appearance: /Solid
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-(Diphenylphosphino)-2'-methylbiphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Diphenylphosphino)-2'-methylbiphenyl(402822-72-4)
• EPA Substance Registry System: 2-(Diphenylphosphino)-2'-methylbiphenyl(402822-72-4)

Safety Data

• Hazardous Substances Data: 402822-72-4(Hazardous Substances Data)

Usage

Uses

suzuki reaction

Upstream product

• 13175-77-4 (2'-methyl-[1,1'-biphenyl]-2-yl)diphenylphosphine oxide 
• 16419-60-6 2-Methylphenylboronic acid 
• 62336-24-7 (2-bromophenyl)diphenylphosphane 
• 583-55-1 1-Bromo-2-iodobenzene 
• 88652-74-8 (2-bromophenyl)diphenylphosphine oxide 
• 251320-87-3 2-bromo-2'-methylbiphenyl 
• 1079-66-9 chloro-diphenylphosphine 
• 829-85-6 diphenylphosphane 
• 4559-70-0 Diphenylphosphine oxide 

Downstream Products

• 13175-77-4 (2'-methyl-[1,1'-biphenyl]-2-yl)diphenylphosphine oxide 
• 1601392-64-6 C₂₇H₂₃O₃P 
• 1351394-96-1 (3^,-methyl-[1,1^,;2^,,1^,,]terphenyl-2^,,-yl)diphenylphosphine 
• 1342879-09-7 1-methyl-5-phenyl-5H-dibenzophosphole 

Relevant articles and documents

Ruthenium-Catalyzed Gram-Scale Preferential C-H Arylation of Tertiary Phosphine

A general protocol for site-preferential mono-C-H arylation of tertiary phosphine ligands catalyzed by a ruthenium(II) complex was devised. This protocol gives access to a series of modified Buchwald-biaryl monophosphines on a gram scale in moderate to excellent yields. A catalytic cycle is proposed derived from knowledge of the intermediates observed by ESI-MS. Importantly, these monoarylated products could be further transformed into dibenzophosphole derivatives.

Palladium-catalyzed P(O)R2 directed C-H arylation to synthesize electron-rich polyaromatic monophosphorus ligands

Palladium-catalyzed arylation of (diisopropylphosphoryl)biphenyl skeleton derivatives by the P(O)R2 directed C-H functionalization was reported. The related products were obtained in high regioselectivity and good functional group tolerance was observed. This reaction provided a new and efficient pathway for the synthesis of polyaromatic monophosphorus ligands. The Royal Society of Chemistry.

Selective arylation of 1,1-disubstituted olefins using a biphenyl-based phosphine in Heck coupling reactions

The biphenyl-based phosphine, 2-diphenylphosphino-2′-methylbiphenyl is an effective ligand for palladium-catalyzed terminal arylation of 1,1-disubstituted olefins with aryl bromides in DMF and K2CO3 as base. The yields of products are independent of the electronic properties of the aryl bromides, however, the nature of the olefin has a major effect.