402943-01-5Relevant articles and documents
Chelated enolates of amino acid esters - New and efficient nucleophiles for isomerization-free, stereoselective palladium-catalyzed allylic substitutions
Kazmaier, Uli,Zumpe, Franz L.
, p. 4067 - 4076 (2007/10/03)
Chelated amino acid ester enolates were found to be suitable nucleophiles for palladium-catalyzed allylic alkylations. Unlike stabilized soft nucleophiles, the chelated enolates react under very mild reaction conditions, even at -78 °C. If TFA protected a