402958-60-5

Upstream product

• 3009-88-9 5-cyanopentanoic acid methyl ester 
• 402958-58-1 3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (3R,5S)-5-methoxycarbonyl-1-[(S)-3-methyl-2-((S)-3-methyl-2-{5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoylamino}-butyrylamino)-butyryl]-pyrrolidin-3-yl ester 
• 402958-47-8 (S)-3-Methyl-2-((S)-3-methyl-2-{5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoylamino}-butyrylamino)-butyric acid 
• 402958-46-7 5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 402958-19-4 5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoic acid methyl ester 
• 402958-20-7 5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoic acid 
• 80486-64-2 methyl 5-(1,2,3,4-tetrazol-5-yl)valerate 
• 402958-32-1 3-amino-N-cyclopropyl-2-hydroxylhexanamide 
• 402958-59-2 3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (3R,5S)-5-carboxy-1-[(S)-3-methyl-2-((S)-3-methyl-2-{5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoylamino}-butyrylamino)-butyryl]-pyrrolidin-3-yl ester 

Downstream Products

• 402958-61-6 3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (3R,5S)-5-(1-cyclopropylaminooxalyl-butylcarbamoyl)-1-[(S)-3-methyl-2-((S)-3-methyl-2-{5-[1-(1-methyl-1-phenyl-ethyl)-1H-tetrazol-5-yl]-pentanoylamino}-butyrylamino)-butyryl]-pyrrolidin-3-yl ester 

Relevant academic research and scientific papers

P4 cap modified tetrapeptidyl α-ketoamides as potent HCV NS3 protease inhibitors

We describe herein the design, syntheses, and biological evaluation of new series of P4 tetrazole and adipic acid, ester, amide capped tetrapeptidyl α-ketoamide based HCV protease inhibitors.