40324-53-6

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 106-44-5 p-cresol 
• 13481-09-9 2-(4-methylphenoxy)tetrahydro-2H-pyran 

Downstream Products

• 2206-43-1 4-methoxyisophthalic acid 
• 117658-57-8 methyl 4-methyl-2-(tetrahydro-2H-pyran-2-yl)phenyl ether 

Relevant academic research and scientific papers

Multidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic prosses utilizing such catalytic compositions

Multidentate phosphite ligands are disclosed for use in reactions such as hydrocyanation and isomerization. The catalyst compositions made therefrom and the various catalytic processes which employ such multidentate phosphite ligands are also disclosed. I

The Thermal ortho-Substitution of Phenols by Vinyl Ethers

Pyrolysis of a mixture of phenol and 3,4-dihydro-2H-pyran (6) at 150-180 deg C resulted in the formation of 2-(tetrahydro-2H-pyran-2-yl)phenol (3a) in moderate yield.This selective ortho-substitution reaction has been investigated for a range of phenols and a number of vinyl ethers.While it was found to be a fairly general reaction for phenols, only with the vinyl ether (6) and 2,3-dihydrofuran (28a) was the reaction found to be regioselective.Aluminium phenylate strongly catalyses the reaction of phenol with (6), which proceeded under these conditions at room temperature.An ene-type mechanism is proposed for the reaction.