40332-58-9 Usage
Description
D-PENTAFLUOROPHE, a member of the pentafluorophenyl compounds, is a chemical compound characterized by its unique structure of a phenyl ring with five fluorine atoms attached. This fluorine-rich composition endows it with distinctive properties, making it a valuable building block in organic synthesis. Its ability to selectively and efficiently introduce fluorine atoms into organic molecules positions D-PENTAFLUOROPHE as a crucial reagent in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.
Uses
Used in Pharmaceutical Synthesis:
D-PENTAFLUOROPHE is used as a reagent for the synthesis of pharmaceuticals, leveraging its capacity to introduce fluorine atoms into organic molecules. This property is particularly valuable in the development of new drugs, as fluorination can significantly alter the pharmacokinetic and pharmacodynamic properties of drug candidates, potentially enhancing their efficacy and safety.
Used in Agrochemical Synthesis:
In the agrochemical industry, D-PENTAFLUOROPHE is utilized as a reagent for the synthesis of agrochemicals. Its ability to selectively fluorinate organic molecules can lead to the creation of more effective and environmentally friendly pesticides and herbicides, contributing to sustainable agricultural practices.
Used in Fine Chemicals Synthesis:
D-PENTAFLUOROPHE is also employed in the synthesis of fine chemicals, where its unique properties allow for the development of high-quality specialty chemicals used in various applications, such as fragrances, dyes, and other industrial chemicals. Its versatility and fluorine-rich structure make it an indispensable component in the organic chemistry toolkit.
Check Digit Verification of cas no
The CAS Registry Mumber 40332-58-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,3,3 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 40332-58:
(7*4)+(6*0)+(5*3)+(4*3)+(3*2)+(2*5)+(1*8)=79
79 % 10 = 9
So 40332-58-9 is a valid CAS Registry Number.
40332-58-9Relevant articles and documents
Method for Preparing Unnatural Amino Acids
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Paragraph 0172; 0173; 0188; 0189, (2017/01/09)
The present invention relates to a manufacturing method of unnatural amino acids and unnatural amino acids manufactured thereby. Specifically, the present invention relates to an asymmetric synthesis method which can manufacture unnatural amino acids having significantly high optical purity, and to the unnatural amino acids manufactured thereby. A manufacturing method of unnatural amino acids represented by chemical formula 6 or chemical formula 7 comprises the steps of: synthesizing a compound represented by chemical formula 4 or chemical formula 5; manufacturing a diol compound; and manufacturing a carboxylic acid compound.COPYRIGHT KIPO 2016
RESOLUTION AND USE IN α-AMINO ACID SYNTHESIS OF IMIDAZOLIDINONE GLYCINE DERIVATIVES
Fitzi, Robert,Seebach, Dieter
, p. 5277 - 5292 (2007/10/02)
The imidazolidinones (rac.-1 and rac.-2) obtained from pivalaldehyde and glycine amides are resolved efficiently by crystallization of diastereomeric ammonium salts with chiral acids (mandelates and a gulonate respectively).The free bases are acylated under Schotten-Baumann conditions to give enantiomerically pure 1-Bz-, 1-BOC-, 1-Z- or 1-formyl-2-t-butyl-3-methyl- or -3-benzyl-4-imidazolidinones.Diastereoselective alkylation of the 3-methyl derivatives (BMI) with a variety of electrophiles (LDA/THF -70 to +25 degC) gives trans-disubstituted imidazolidinones exclusively (3-22).Some of these are hydrolyzed by a procedure employing excess acidic ion exchange resin to give enantiomerically pure (R)- or (S)-amino acids.The procedure is compared with other methods of generating chiral glycine enolates.
