403478-34-2 Usage
Molecular structure
1-Pyrrolidinecarboxylic acid, 2-[(phenylamino)carbonyl]-, 9H-fluoren-9-ylmethyl ester, (2S)is an ester derivative of 1-pyrrolidinecarboxylic acid with a phenylaminocarbonyl group and a 9H-fluoren-9-ylmethyl ester group.
Chirality
The (2S)configuration indicates that the compound is chiral, meaning it has non-superimposable mirror images (enantiomers) that can interact differently with biological targets.
Bioavailability
The presence of the 9H-fluoren-9-ylmethyl ester group enhances the bioavailability of the compound, making it more easily absorbed and utilized by the body.
Stability
The 9H-fluoren-9-ylmethyl ester group also adds stability to the compound, increasing its resistance to degradation and improving its shelf life.
Pharmaceutical applications
Due to its unique structure and properties, this chemical compound has potential applications in the field of pharmaceuticals, particularly in the development of new drugs and bioactive molecules with improved properties and efficacy.
Stereochemical effects
As a chiral compound, it may exhibit different biological activities and pharmacokinetics depending on its stereochemistry, which can be important for drug design and development.
Check Digit Verification of cas no
The CAS Registry Mumber 403478-34-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,3,4,7 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 403478-34:
(8*4)+(7*0)+(6*3)+(5*4)+(4*7)+(3*8)+(2*3)+(1*4)=132
132 % 10 = 2
So 403478-34-2 is a valid CAS Registry Number.
403478-34-2Relevant academic research and scientific papers
Kanemitsu, Takuya,Umehara, Atsushi,Haneji, Rieko,Nagata, Kazuhiro,Itoh, Takashi
, p. 3893 - 3898 (2012)
A simple and inexpensive proline-based organocatalyst was developed for the reduction of imines using trichlorosilane as a reductant. The reduction of N-aryl imines in the presence of 10 mol % of N-pivaloyl-l-proline anilide was carried out to give the co
Discovery and structure-activity relationships of urea derivatives as potent and novel CCR3 antagonists
Nitta, Aiko,Iura, Yosuke,Tomioka, Hiroki,Sato, Ippei,Morihira, Koichiro,Kubota, Hirokazu,Morokata, Tatsuaki,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi,Imaoka, Takayuki,Takahashi, Toshiya
scheme or table, p. 4951 - 4954 (2012/08/28)
The synthesis and structure-activity relationships of ureas as CCR3 antagonists are described. Optimization starting with lead compound 2 (IC 50 = 190 nM) derived from initial screening hit compound 1 (IC 50 = 600 nM) led to the iden
