403507-06-2

Upstream product

• 403507-04-0 ethyl (2E,4E)-2-methyl-5-iodopenta-2,4-dienoate 
• 250595-69-8 {1-allyl-2-[2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-carbamic acid tert-butyl ester 
• 250595-63-2 (3aR,6aS)-6a-Allyl-1-((R)-2-hydroxy-1-phenyl-ethyl)-hexahydro-cyclopenta[b]pyrrol-2-one 
• 250595-68-7 [(1S,2R)-1-Allyl-2-((R)-2-hydroxy-1-methyl-ethyl)-cyclopentyl]-carbamic acid tert-butyl ester 
• 250595-66-5 6a-allyl-3-methyl-2-oxo-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid tert-butyl ester 
• 250595-65-4 6a-allyl-2-oxo-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid tert-butyl ester 
• 250595-64-3 (3aR,6aS)-6a-Allyl-hexahydro-cyclopenta[b]pyrrol-2-one 
• 161779-70-0 (3R,5aR,8aS)-3-phenyl-hexahydro-1-oxa-3a-aza-cyclopenta[c]pentalen-4-one 
• 403507-05-1 (2E,4E)-8-{(1R,2R)-1-tert-Butoxycarbonylamino-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-2-methyl-octa-2,4-dienoic acid ethyl ester 

Downstream Products

• 403507-08-4 (E)-4-[(1R,5S,7R)-1-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester 
• 403507-07-3 (E)-4-{(1R,5S,7R)-1-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-6-aza-spiro[4.5]dec-7-yl}-2-methyl-but-2-enoic acid ethyl ester 

Relevant academic research and scientific papers

Concise stereoselective routes to advanced intermediates related to natural and unnatural pinnaic acid

Important intermediates: In an effort to synthesize and determine the stereo-chemistry of pinnaic acid, C14-epimeric aldehydes 1 and 2 were generated from Meyers' lactam 3. A key step in the parallel syntheses is a highly stereoselective vinylogous Michae