403511-57-9

Upstream product

• 149707-75-5 2,3,4,6-tetra-O-benzoyl-1-O-trichloroacetimidoyl-α-D-galactopyranose 
• 403511-55-7 Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-(5-hydroxy-2-nitro-benzyloxy)-tetrahydro-pyran-4-yl ester 
• 10022-13-6 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 
• 60463-12-9 3-hydroxymethyl-4-nitrophenol 

Downstream Products

• 403511-60-4 N-{(2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-2-[2-nitro-5-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-benzyloxy]-tetrahydro-pyran-3-yl}-acetamide 

Relevant academic research and scientific papers

Novel substrates for efficient enzymatic transglycosylation by Bacillus circulans

To develop transglycosylation for efficient preparation of N-acetyllactosamine (Galβ 1→4)GlcNAc, LacNAc), β-galactosidase mediated transglycosylation using novel substrates Bacillus Circulans was explored. To make transglycosylation entropically favorable

β-Galactosidase-catalyzed intramolecular transglycosylation

A novel transglycosylation strategy for efficient preparation of N-acetyllactosamine (Galβl→4GlcNAc, LacNAc) and sialyl LacNAc was developed using β-galactosidase from Bacillus circulans. In order to minimize the competing hydrolysis by forcing the enzyma