Cas 403518-92-3,(S)-2-((S)-2-Acetylamino-5-guanidino-pentanoylamino)-6-amino-hexanoic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-(4-carbamoylmethyl-2-oxo-2H-chromen-7-ylcarbamoyl)-pentylcarbamoyl]-2-methyl-propylcarbamoyl}-3-methyl-butylcarbamoyl)-2-hydroxy-ethyl]-amide

403518-92-3

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Basic information

Product Name: (S)-2-((S)-2-Acetylamino-5-guanidino-pentanoylamino)-6-amino-hexanoic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-(4-carbamoylmethyl-2-oxo-2H-chromen-7-ylcarbamoyl)-pentylcarbamoyl]-2-methyl-propylcarbamoyl}-3-methyl-butylcarbamoyl)-2-hydroxy-ethyl]-amide
Synonyms: (S)-2-((S)-2-Acetylamino-5-guanidino-pentanoylamino)-6-amino-hexanoic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-(4-carbamoylmethyl-2-oxo-2H-chromen-7-ylcarbamoyl)-pentylcarbamoyl]-2-methyl-propylcarbamoyl}-3-methyl-butylcarbamoyl)-2-hydroxy-ethyl]-amide
CAS NO:403518-92-3
Molecular Formula:
Molecular Weight: 957.14
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-2-((S)-2-Acetylamino-5-guanidino-pentanoylamino)-6-amino-hexanoic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-(4-carbamoylmethyl-2-oxo-2H-chromen-7-ylcarbamoyl)-pentylcarbamoyl]-2-methyl-propylcarbamoyl}-3-methyl-butylcarbamoyl)-2-hydroxy-ethyl]-amide(CAS DataBase Reference)
NIST Chemistry Reference: (S)-2-((S)-2-Acetylamino-5-guanidino-pentanoylamino)-6-amino-hexanoic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-(4-carbamoylmethyl-2-oxo-2H-chromen-7-ylcarbamoyl)-pentylcarbamoyl]-2-methyl-propylcarbamoyl}-3-methyl-butylcarbamoyl)-2-hydroxy-ethyl]-amide(403518-92-3)
EPA Substance Registry System: (S)-2-((S)-2-Acetylamino-5-guanidino-pentanoylamino)-6-amino-hexanoic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-(4-carbamoylmethyl-2-oxo-2H-chromen-7-ylcarbamoyl)-pentylcarbamoyl]-2-methyl-propylcarbamoyl}-3-methyl-butylcarbamoyl)-2-hydroxy-ethyl]-amide(403518-92-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 403518-92-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 403518-92-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,3,5,1 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 403518-92:
(8*4)+(7*0)+(6*3)+(5*5)+(4*1)+(3*8)+(2*9)+(1*2)=123
123 % 10 = 3
So 403518-92-3 is a valid CAS Registry Number.

403518-92-3Upstream product

403518-92-3Downstream Products

403518-92-3Relevant academic research and scientific papers

Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore

Maly, Dustin J.,Leonetti, Francesco,Backes, Bradley J.,Dauber, Deborah S.,Harris, Jennifer L.,Craik, Charles S.,Ellman, Jonathan A.

, p. 910 - 915 (2002)

A highly efficient solid-phase synthesis method for the preparation of fluorogenic protease substrates based upon the bifunctional leaving group 7-amino-4-carbamoylmethylcoumarin (ACC) is reported. Methods for the large-scale preparation of the novel fluorogenic leaving-group ACC are provided (Scheme 1). Detailed procedures are also provided for loading a diverse set of amino acids to support-bound ACC in good yields and with minimal racemization. Finally, procedures are included for the preparative synthesis of optimized ACC substrates for HIV-1 protease and plasmin.

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